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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">278951</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">IRRITABLE BOWEL SYNDROME: PATHOGENETIC APPROACH TO THE TREATMENT OF ABDOMINAL PAIN</article-title><trans-title-group xml:lang="ru"><trans-title>СИНДРОМ РАЗДРАЖЕННОГО КИШЕЧНИКА: ПАТОГЕНЕТИЧЕСКИЕ ПОДХОДЫ К ЛЕЧЕНИЮ АБДОМИНАЛЬНОЙ БОЛИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Butorova</surname><given-names>Lyudmila Ivanovna</given-names></name><name xml:lang="ru"><surname>Буторова</surname><given-names>Людмила Ивановна</given-names></name></name-alternatives><bio xml:lang="ru"><p>ГУЗ ПК № 209</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kalinin</surname><given-names>Andrey Vladimirovich</given-names></name><name xml:lang="ru"><surname>Калинин</surname><given-names>Андрей Владимирович</given-names></name></name-alternatives><bio xml:lang="ru"><p>ГИУВ МО РФ</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Butorova</surname><given-names>L I</given-names></name><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Kalinin</surname><given-names>A V</given-names></name><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГУЗ ПК № 209</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГИУВ МО РФ</institution></aff></aff-alternatives><aff id="aff3"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2011-06-20" publication-format="electronic"><day>20</day><month>06</month><year>2011</year></pub-date><volume>18</volume><issue>12</issue><issue-title xml:lang="en">NO12 (2011)</issue-title><issue-title xml:lang="ru">№12 (2011)</issue-title><fpage>106</fpage><lpage>111</lpage><history><date date-type="received" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО «Бионика Медиа»</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/278951">https://journals.eco-vector.com/2073-4034/article/view/278951</self-uri><abstract xml:lang="en"><p>The article considers the basic mechanisms of pain in irritable bowel syndrome (IBS), discusses the role of spasmolytics in the treatment of IBS. The results of a clinical study on the efficacy of monotherapy with calcium channel blocker pinaverium bromide (Dicetel) in patients with IBS and abdominal pain are presented.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассматриваются основные механизмы формирования болевого синдрома при синдроме раздраженного кишечника (СРК); обсуждается роль спазмолитиков в лечении СРК. Представлены результаты клинического исследования по оценке эффективности монотерапии абдоминального болевого синдрома при СРК блокатором кальциевых каналов пинаверия бромидом (Дицетел).</p></trans-abstract><kwd-group xml:lang="en"><kwd>irritable bowel syndrome</kwd><kwd>spasmolytic therapy</kwd><kwd>pinaverium bromide</kwd><kwd>Dicetel</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром раздраженного кишечника</kwd><kwd>спазмолитическая терапия</kwd><kwd>пинаверия бромид</kwd><kwd>Дицетел</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ардатская М.Д. Синдром раздраженного кишечника. Клиническая лекция // Consilium medicum 2010. № 8. С. 48-54.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Маев И.В., Самсонов А.А. и др. Синдром раздраженного кишечника, актуальность проблемы и вопросы современной терапии // Фарматека, 2011. № 2(214). 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