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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">278985</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">PROBIOTIC PRODUCTS IN CLINICAL PRACTICE</article-title><trans-title-group xml:lang="ru"><trans-title>ПРОБИОТИЧЕСКИЕ ПРОДУКТЫ В КЛИНИЧЕСКОЙ ПРАКТИКЕ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolaeva</surname><given-names>Svetlana Viktorovna</given-names></name><name xml:lang="ru"><surname>Николаева</surname><given-names>Светлана Викторовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЦНИИ эпидемиологии Роспотребнадзора</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Nikolaeva</surname><given-names>S V</given-names></name><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ЦНИИ эпидемиологии Роспотребнадзора</institution></aff></aff-alternatives><aff id="aff2"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2011-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2011</year></pub-date><volume>18</volume><issue>15</issue><issue-title xml:lang="en">NO15 (2011)</issue-title><issue-title xml:lang="ru">№15 (2011)</issue-title><fpage>56</fpage><lpage>57</lpage><history><date date-type="received" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО «Бионика Медиа»</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/278985">https://journals.eco-vector.com/2073-4034/article/view/278985</self-uri><abstract xml:lang="en"><p>The article justifies the use of probiotic fermented milk foods for purposes of maintenance of microecology of the human gastrointestinal tract. The most common basis for their creation is traditional fermented milk products enriched by strains of probiotic microorganisms, mainly bifidobacteria and lactobacillus. The clinical studies confirming the usefulness of probiotic products Actimel and Activia are presented. It is emphasized that probiotic fermented milk products can be widely used among both healthy and sick people as a treatment and prevention of a number of diseases.</p></abstract><trans-abstract xml:lang="ru"><p>Обосновывается использование кисломолочных пробиотических продуктов питания в целях поддержания микроэкологии желудочно-кишечного тракта человека. Чаще всего в качестве основы для их создания используются традиционные кисломолочные продукты, обогащенные штаммами пробиотических микроорганизмов - преимущественно бифидо- и лактобактерий. Приводятся данные клинических исследований, подтвердивших полезность для человека пробиатических продуктов Actimel и Активиа. Подчеркивается, что пробиотические кисломолочные продукты можно широко применять среди как здоровых, так и больных людей в качестве лечения и профилактики целого ряда заболеваний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Actimel</kwd><kwd>gastrointestinal tract</kwd><kwd>intestinal microflora</kwd><kwd>probiotic fermented milk products</kwd><kwd>Actimel</kwd><kwd>Activia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>желудочно-кишечный тракт</kwd><kwd>микрофлора кишечника</kwd><kwd>кисломолочные пробиотические продукты</kwd><kwd>Активиа</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Pedone CA, et al. Multicentric study of the effect of milk fermented by Lactobacillus casei on the incidence of diarrhoea. Int J Clin Prac 2000;54(9):568-71.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Горелов А.В., Усенко Д.В., Елезова Л.И. и др. Использование пробиотических продуктов в лечении кишечных инфекций у детей // Вопросы современной педиатрии 2005. № 2 (4). С. 47-52.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Горелов А.В., Усенко Д.В. Влияние пробиотического продукта "Актимель" на состояние здоровья детей // Вопросы современной педиатрии 2003. № 4 (2). С. 87-90.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Guillemard E, Tondu F, Lacoin F, Schrezenmeir J. Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial. Br J Nutr 2010;103(1):58-68.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Sykora J, Malan A, Zahlava J, et al. Gastric emptying of solids in children with H. pylori-positive and H. pylori-negative non-ulcer dyspepsia. J Pediatr Gastroenterol Nutr 2004;39:246-52.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Hickson M, D'Souza A, Muthu N, et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ 2007;335:80-5.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Aubin JT, Remigy M, Verseil L et al. Пробиотический ферментированный молочный продукт усиливает иммунный ответ на противогриппозную вакцинацию у пожилых людей / Международный конгресс по иммунологии (ICI), Рио-де-Жанейро, Бразилия, август 2007 г.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Parra D, De Morentin BM, Cobo JM, Mateos A, Martinez JA. Monocyte function in healthy middle-aged people receiving fermented milk containing Lactobacillus casei. J Nutr Health Aging 2004;8(4):208-11.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Berrada N, Lemeland JF, Laroche G, Thouvenot P, Piaia M. Bifidobacterium from fermented milks: Survival during gastric transit. J Dairy Sci 1991;74:409-13.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Pochart P, Marteau P, Bouhnik Y, et al. Survival of Bifidobacteria ingested via fermented milk during their passage through the human small intestine: an in vivo study using intestinal perfusion. Am J Clin Nutr 1992;55:78-80.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Парфенов А.И., Ручкина И.Н. Профилактика и лечение запоров пробиотиками // Фарматека 2006. № 12 (127). С. 23-29.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Лазебник Л.Б., Парфенов А.И., Усенко Д.В., Прилепская С.И. Роль кисломолочных пробиотических продуктов в коррекции умеренных нарушений пищеварения // Consilium medicum, 2008. № 10(8). С. 73-76.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Guyonett D, Chassany O, Ducrotte P, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther 2007;26:475-86.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Meanse S, et al. Recent advances in the use of functional foods: effects of the commercial fermented milk with Bifidobacterium animalis strain DN-173 010 and yogurt strains on gut transit time in the elderly. Microb Ecol Health Dis 2003;15:15-22.</mixed-citation></ref></ref-list></back></article>
