<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">278991</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE CHOICE OF LAXATIVES: PLACE OF STIMULANT LAXATIVES IN THE TREATMENT OF CONSTIPATION</article-title><trans-title-group xml:lang="ru"><trans-title>ПРАВИЛА ВЫБОРА СЛАБИТЕЛЬНЫХ СРЕДСТВ: НИША СТИМУЛИРУЮЩИХ СЛАБИТЕЛЬНЫХ В ЛЕЧЕНИИ ЗАПОРА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belousova</surname><given-names>Elena Aleksandrovna</given-names></name><name xml:lang="ru"><surname>Белоусова</surname><given-names>Елена Александровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФУВ МОНИКИ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Podlesskikh</surname><given-names>Marina Nikolaevna</given-names></name><name xml:lang="ru"><surname>Подлесских</surname><given-names>Марина Николаевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>МОНИКИ</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tsodikova</surname><given-names>Ol'ga Markovna</given-names></name><name xml:lang="ru"><surname>Цодикова</surname><given-names>Ольга Марковна</given-names></name></name-alternatives><bio xml:lang="ru"><p>МОНИКИ</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Belousova</surname><given-names>E A</given-names></name><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Podlesscikh</surname><given-names>M N</given-names></name><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Tcodikova</surname><given-names>O M</given-names></name><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФУВ МОНИКИ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">МОНИКИ</institution></aff></aff-alternatives><aff id="aff3"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2011-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2011</year></pub-date><volume>18</volume><issue>15</issue><issue-title xml:lang="en">NO15 (2011)</issue-title><issue-title xml:lang="ru">№15 (2011)</issue-title><fpage>87</fpage><lpage>92</lpage><history><date date-type="received" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО «Бионика Медиа»</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/278991">https://journals.eco-vector.com/2073-4034/article/view/278991</self-uri><abstract xml:lang="en"><p>The article considers modern views on the types of constipation, presents the treatment approaches taking into account features of development of constipation and its pathogenic characteristics, and provides a detailed classification of laxatives with the description of their mechanisms of action. The authors propose an algorithm of treatment of constipation and selection of laxatives based on the etiopathogenetic parameters of constipation. The advantages and disadvantages of different groups of laxatives are described; correct use of stimulant laxatives is emphasized.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассмотрены современные представления о видах запоров, представлены подходы к лечению с учетом особенностей развития запора и его патогенетических характеристик, приведена подробная классификация слабительных средств с описанием механизмов их действия. Авторы предлагают алгоритм лечения запора и правила выбора слабительных средств с учетом этиопатогенетических параметров запора. Описаны достоинства и недостатки разных групп слабительных, сделан акцент на правильном использовании стимулирующих слабительных.</p></trans-abstract><kwd-group xml:lang="en"><kwd>constipation</kwd><kwd>laxatives</kwd><kwd>stimulant laxatives</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>запор</kwd><kwd>слабительные средства</kwd><kwd>стимулирующие слабительные</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Constipation. Ed. Kamm MA, Lennard-Jones JE Wrightson Biomedical Publishing LTD, USA,1994</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Thompson WG. The road to Rome III. Gastroenterology 2006;130(5):1466-79.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Thompson WG, Longstreth GF, Drossman DA, et al. Functional bowel disorders and functional abdominal pain. Gut 1999;45(suppl. 11):II43.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Bharucha АЕ. Constipation. Best Pract Res Clin Gastroenterol 2007;21(4):709-31.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Белоусова Е.А. Запор в пожилом возрасте // Врач. 2002. № 5. С. 34-36.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Пасечников В.Д. Современные представления об этиологии, патофизиологии и лечении функционального запора // Клинические перспективы в гастроэнтерологии и гепатологии. 2003. № 2. С. 24-30.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Corazziari E, Badiali D. Approach to the patient with chronic constipation: аpproach to the patient with chronic gastrointestinal disorders. Ed. Corazziari E. Solvay pharmaceuticals 2000, p. 341-54.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Wingate D, Hongo M, Kellow J, al. Disorders of gastrointestinal motility: towards a new classification. J Gastroenterol Hepatol 2002;17(Suppl):SI-S14.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Rao S. Constipation: Evaluation and Treatment of Colonic and Anorectal Motility Disorders. Gastrointest Endoscopy Clin N Am 2009;19:117-39.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Kamm M. Clinical Management. Clinical Case: Chronic Constipation. Gastroenterology 2006;131:.233-9.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Tariq S. Constipation in Long-Term Care. Review. J Am Med Dir Assoc 2007;8:209-18.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Fleming V, Wade Е. A Review of Laxative Therapies for Treatment of Chronic Constipation in Older Adult. Am J Geriatr Pharmacother 2010;8:514-50.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Allescher HD. Laxatives and Prokinetics- Good or bad. Falk symposium № 95, 1996, p. 121-29.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Hallmann F. Toxity of commonly used laxatives. Med Sci Monit 2000;6(3):618-28.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Muller-Lissner S. The difficult patient with constipation. Best Pract Res Clin Gastroenterol 2007;.21:473-84.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Shiller LR. Review article: the therapy of constipation. Aliment Pharmacol Ther 2001;15:749-63.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Singh S, Rao S. Pharmacologic Management of Chronic Constipation. Gastroenterol Clin N Am 2010;39:509-27.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>American College of Gastroenterology Chronic Constipation Task Force. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol 2005;100:S1-S22.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Miles C, Fellowes D, Goodman ML, Wilkinson S. Laxatives for the management of constipation in palliative care patients. Cochrane Database Syst Rev 2006;18(4):CD003448.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Mueller-Lissner S, Kamm MA, Wald A, et al. Multicenter, 4-week, double-blind,randomized, placebo-controlled trial of sodium picosulfate in patients with chronic constipation. Am J Gastroenterol 2010;105:897-903.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Remes-Troche J, Rao S. Defecation disoders: newromuscular aspects and Treatment. Curr Gastroenterol Rep 2006;8:291-99.</mixed-citation></ref></ref-list></back></article>
