PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media279895ArticlesСтатьиResearch ArticleLechenie ostrogo bronkhiolita u deteyЛечение острого бронхиолита у детейPatrushevaYu. SПатрушеваЮ. СНЦЗД РАМН150820121915NO15 (2012)№15 (2012)566124022023Copyright ©; 2012, Bionika MediaCopyright ©; 2012, ООО «Бионика Медиа»2012Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/279895

Acute bronchiolitis is a widespread disease and one of the leading causes of hospitalization and death among infants. Measures aimed to ensuring adequate oxygenation and water balance in patients with bronchiolitis are generally recognized. The effectiveness of all other existing methods for the treatment of acute bronchiolitis is a subject for serious debate. Development of causal treatment of viral lower respiratory tract infections is underway. The therapeutic antibody to RS-(respiratory syncytial) virus, palivizumab, is currently used for prevention of RS-virus bronchiolitis in children with severe comorbidities. Inhaled β-agonists relieve the symptoms of bronchial obstruction, but do not affect the duration of the disease, the frequency of hospitalization and length of hospital stay in children. Hypertonic solution of sodium chloride is promising according to the results of many international studies. We present your own successful experience of treatment of bronchiolitis with inhaled bronchodilators in combination with a 3 % sodium chloride.

Острый бронхиолит распространен очень широко, является одной из основных причин госпитализации и смертности среди детей раннего возраста. Общепризнанными являются лишь мероприятия, направленные на обеспечение адекватной оксигенации и водного баланса у пациентов с бронхиолитом. Эффективность всех остальных существующих методов лечения острого бронхиолита -предмет серьезных дискуссий. Ведутся работы над созданием этиотропной терапии вирусных инфекций нижних дыхательных путей. Препарат моноклональных антител к РС-(респираторно-синцитиальному)-вирусу паливизумаб уже используется для профилактики РС-вирусного бронхиолита у детей с тяжелыми сопутствующими заболеваниями. Ингаляционные β-адреномиметики облегчают симптомы бронхообструктивного синдрома, но не влияют на длительность болезни, частоту и сроки госпитализации детей. Перспективным по результатам многих зарубежных исследований является гипертонический раствор натрия хлорида. Мы представляем собственный успешный опыт лечения бронхиолита с использованием бронхолитических ингаляций в сочетании с 3 %-ным раствором натрия хлорида.

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