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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">282388</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Effektivnyy i bezopasnyy kontrol' glikemii s pomoshch'yu Diabetona MV: zalog uspeshnoy profilaktiki khronicheskikh oslozhneniy sakharnogo diabeta 2 tipa</article-title><trans-title-group xml:lang="ru"><trans-title>Эффективный и безопасный контроль гликемии с помощью Диабетона МВ: залог успешной профилактики хронических осложнений сахарного диабета 2 типа</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Biryukova</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Бирюкова</surname><given-names>Е. В</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н, проф. кафедры эндокринологии и диабетологии</p></bio><email>lena@obsudim.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Danilova</surname><given-names>T. B</given-names></name><name xml:lang="ru"><surname>Данилова</surname><given-names>Т. Б</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра эндокринологии и диабетологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">МГМСУ им. А.И. Евдокимова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-08-20" publication-format="electronic"><day>20</day><month>08</month><year>2013</year></pub-date><volume>20</volume><issue>16</issue><issue-title xml:lang="en">NO16 (2013)</issue-title><issue-title xml:lang="ru">№16 (2013)</issue-title><fpage>14</fpage><lpage>19</lpage><history><date date-type="received" iso-8601-date="2023-02-25"><day>25</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО «Бионика Медиа»</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/282388">https://journals.eco-vector.com/2073-4034/article/view/282388</self-uri><abstract xml:lang="en"><p>Prevention of micro- and macrovascular complications of type 2 diabetes mellitus is an important goal of modern medicine. The article discusses the issues of treatment of the disease, the pharmacological characteristics, efficacy, and safety of sulfonylurea medications; the main benefits of gliclazide are described. The results of international studies that have demonstrated that the use of gliclazide contributes not only to the long-term metabolic control, but also to prevention or delay of development of vascular complications, are presented.</p></abstract><trans-abstract xml:lang="ru"><p>Предотвращение микро- и макрососудистых осложнений сахарного диабета 2 типа - важная задача современной медицины. Обсуждаются вопросы терапии заболевания, фармакологические характеристики, эффективность, безопасность препаратов сульфонилмочевины; отражены основные преимущества гликлазида. Приводятся результаты международных исследований, которые продемонстрировали, что применение гликлазида способствует не только обеспечению долгосрочного метаболического контроля, но и предотвращению или отсрочке развития сосудистых осложнений.</p></trans-abstract><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>hypoglycemia</kwd><kwd>macro- and microvascular complications</kwd><kwd>sulfonylurea medications</kwd><kwd>gliclazide</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>гипогликемии</kwd><kwd>макро- и микрососудистые осложнения</kwd><kwd>препараты сульфонилмочевины</kwd><kwd>гликлазид</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Fonseca VA. Defining and Characterizing the Progression of Type 2 Diabetes. Diabetes Care 2009;32(suppl 2):151-56.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ruigomez A, Rodrigues LA. 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