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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">286704</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Taktika vedeniya beremennosti pri preinvazivnom rake sheyki matki</article-title><trans-title-group xml:lang="ru"><trans-title>Тактика ведения беременности при преинвазивном раке шейки матки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ul'rikh</surname><given-names>E. A</given-names></name><name xml:lang="ru"><surname>Ульрих</surname><given-names>Е. А</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф. кафедры онкологии ГБОУ ВПО СЗГМУим. И.И. Мечникова Минздрава России, проф. кафедры детской гинекологии и женской репродуктологии ГБОУ ВПО СПбГПМУ Минздрава России</p></bio><email>elenaulrikh@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Verbitskaya</surname><given-names>E. A</given-names></name><name xml:lang="ru"><surname>Вербитская</surname><given-names>Е. А</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирантка кафедры онкологии</p></bio><email>krey_evgeniya@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Urmancheeva</surname><given-names>A. F</given-names></name><name xml:lang="ru"><surname>Урманчеева</surname><given-names>А. Ф</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., кафедры онкологии</p></bio><email>adaurm@yandex.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kutusheva</surname><given-names>G. F</given-names></name><name xml:lang="ru"><surname>Кутушева</surname><given-names>Г. Ф</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., кафедры детской гинекологии и женской репродуктологии</p></bio><email>fpk@chadogyn.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО СЗГМУ им. И.И. Мечникова Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="ru">ГБОУ ВПО СПбГПМУ Минздрава России</institution></aff><aff><institution xml:lang="en"></institution></aff></aff-alternatives><aff id="aff3"><institution>ГБОУ ВПО СЗГМУ им. И.И. Мечникова Минздрава России</institution></aff><pub-date date-type="pub" iso-8601-date="2014-02-20" publication-format="electronic"><day>20</day><month>02</month><year>2014</year></pub-date><volume>21</volume><issue>4</issue><issue-title xml:lang="en">NO4 (2014)</issue-title><issue-title xml:lang="ru">№4 (2014)</issue-title><fpage>68</fpage><lpage>70</lpage><history><date date-type="received" iso-8601-date="2023-02-26"><day>26</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ООО «Бионика Медиа»</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/286704">https://journals.eco-vector.com/2073-4034/article/view/286704</self-uri><abstract xml:lang="en"><p>Diagnosis of cancer during pregnancy is the dramatic event and difficult dilemma for the pregnant woman, her family and physicians. In the last decade, combination of malignancies with pregnancy becomes less rare event with a frequency of occurrence of 0.05 to 0.10 % of pregnancies. This is due to the postponement of childbearing age, and some decrease in cases of malignant tumors. The most frequent neoplasma, combined with pregnancy, is preinvasive cervical cancer (cervical intraepithelial neoplasia, CIN). The article is dedicated to the review of permissible methods of diagnosis; a possible treatment strategy for patients in accordance with international recommendations and the Russian experience is suggested.</p></abstract><trans-abstract xml:lang="ru"><p>Диагноз рака во время беременности - это драматичное событие, представляющее трудную дилемму для беременной пациентки, ее семьи и лечащих врачей. За последнее десятилетие сочетание злокачественных опухолей с беременностью становится менее редким событием с частотой встречаемости от 0,05 до 0,10 % беременностей. Это связано с отсрочкой деторождения и некоторым снижением возраста заболевших злокачественными опухолями. К наиболее часто встречаемым новообразованиям, сочетающимся с беременностью, относится преинвазивный рак шейки матки (cervical intraepithelial neoplasia, CIN). Статья посвящена обзору допустимых методов диагностики, предложена возможная тактика лечения пациенток в соответствии с международными рекомендациями и российским опытом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cervical cancer</kwd><kwd>cervical intraepithelial neoplasia</kwd><kwd>human papilloma virus</kwd><kwd>pregnancy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак шейки матки</kwd><kwd>цервикальная интраэпителиальная неоплазия</kwd><kwd>вирус папилломы человека</kwd><kwd>беременность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Smith L.H., et al. Cancer associated with obstetric delivery: results of linkage with the California cancer registry. Am. J. Obstet. Gynecol. 2003;189(4):1128-35.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Takushi M., Moromizato H., Sakumoto K., Kanazawa K. Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment. Gynecol Oncol. 2002;87:185-89.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Al-Halal H., Kezouh A., Abenhaim H. Incidence and obstetrical outcomes of cervical intraepithelial neoplasia and cervical cancer in pregnancy: A population-based study on 8.8 million births. Arch. Gynecol. Obstet. 2013;28(2):245-50.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>OECD Family Database www.oecd.org/social/ family/database</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Злокачественные новообразования в России в 2011 г. (заболеваемость и смертность) / Под ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М., 2013. 289 с.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Ostor A.G. Natural history of cervical intraepithelial neoplasia : a critical review. Int. J. Gynecol. Pathol. 1993;12:186-92.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Урманчеева А.Ф., Ульрих Е.А. Опухоли женских половых органов и беременность. Пособие для врачей. СПб., 2011. 40 с.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Dunn T., Bajaj J., Stamm C., Beaty B. Management of the minimally abnormal papanicolaou smear in pregnancy. J. Low Genit. Tract. Dis. 2001;5:133-37.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Apgar B., Kittendorf A., Bettcher C., Wong J., Kaufman A. Update on ASCCP consensus guidelines for abnormal cervical screening tests and cervical histology. Am. Fam. Physician. 2009;80:147-55.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Урманчеева А.Ф. Рак шейки матки и беременность. Практическая онкология. 2002;3(3):183-93.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Paraskevaidis E., Koliopoulos G., Kalantaridou S., et al. Management and evolution of cervical intraepithelial neoplasia during pregnancy and postpartum. Eur. J. Obstet. Gynecol. Reprod. Biol. 2002;104:67-9.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Brinton L.A., Reeves W.C., Brenes M.M., et al. Parity as a risk factor for cervical cancer. Am. J. Epidemiol. 1989;130:486-96.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Bosch A., Marcial V.A. Carcinoma of the uterine cervix associated with pregnancy. Am. J. Roentgenol. Radium. Ther. Nucl. Med. 1966;96:92-9.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Ahdoot D., et al. The effect of route of delivery on regression of abnormal cervical cytologic findings in the postpartum period. Am. J. Obstet. Gynecol. 1998;178:1116-20.</mixed-citation></ref></ref-list></back></article>
