PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media287538ArticlesСтатьиResearch ArticleSovremennoe lechenie revmatoidnogo artrita: rekomendatsii i real'naya praktikaСовременное лечение ревматоидного артрита: рекомендации и реальная практикаChichasovaN. VЧичасоваН. В

д.м.н., проф. кафедры ревматологии ИПО

kafedrarheum@yandex.ruImametdinovaG. RИмаметдиноваГ. Р

доцент кафедры ревматологии ИПО

ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» Минздрава России101020142119NO19 (2014)№19 (2014)364226022023Copyright ©; 2014, Bionika MediaCopyright ©; 2014, ООО «Бионика Медиа»2014Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/287538

To date, the treatment of rheumatoid arthritis (RA) has some success. The emergence of new diagnostic criteria 2010 for RA, implementation of the principles of controlled treatment in practice - strategy of treatment of RA to achieve the goal, the emergence of new forms of previously used disease modifying anti-rheumatic drugs (DMARDs) and new generation preparations (genetically engineered biological agents and the targeted synthetic DMARDs - tofacitinib), allows to approach to personalized treatment of RA and the prevention of adverse outcomes. The widespread introduction of the subcutaneous form of methotrexate into clinical practice, a highly effective drug in relation to the activity and progression in early RA, well tolerated for a long time, allows to achieve the goal for most patients after 6-12 months of therapy using the principles of controlled treatment.

К настоящему времени в лечении ревматоидного артрита (РА) достигнуты определенные успехи. Появление новых диагностических критериев РА 2010 г., внедрение в практику принципов контролируемого лечения (стратегии лечения РА до достижения цели), появление новых форм ранее применяемых базисных противовоспалительных препаратов (БПВП) и препаратов нового поколения (генно-инженерных биологических препаратов и таргетного синтетического БПВП - тофацитиниба), дают возможность клиницисту приблизиться к персонифицированной терапии РА и предотвращению неблагоприятных исходов заболевания. Широкое внедрение в клиническую практику подкожной формы метотрексата, обладающей высокой эффективностью в отношении активности и прогрессирования при раннем РА, длительной хорошей переносимостью, позволяет при использовании принципов контролируемого лечения достигать цели большинству больных через 6-12 месяцев терапии.

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