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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">288340</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">OSTEOPOROZ POSLE INSUL'TA: OSOBENNOSTI RAZVITIYa, DIAGNOSTIKI I LEChENIYa</article-title><trans-title-group xml:lang="ru"><trans-title>ОСТЕОПОРОЗ ПОСЛЕ ИНСУЛЬТА: ОСОБЕННОСТИ РАЗВИТИЯ, ДИАГНОСТИКИ И ЛЕЧЕНИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Karpova</surname><given-names>N. Yu</given-names></name><name xml:lang="ru"><surname>Карпова</surname><given-names>Н. Ю</given-names></name></name-alternatives><email>karpovany@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rashid</surname><given-names>M. A</given-names></name><name xml:lang="ru"><surname>Рашид</surname><given-names>М. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pogonchenkova</surname><given-names>I. V</given-names></name><name xml:lang="ru"><surname>Погонченкова</surname><given-names>И. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО РНИМУ им. Н.И. Пирогова Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская больница № 56»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-10-10" publication-format="electronic"><day>10</day><month>10</month><year>2015</year></pub-date><volume>22</volume><issue>19</issue><issue-title xml:lang="en">NO19 (2015)</issue-title><issue-title xml:lang="ru">№19 (2015)</issue-title><fpage>14</fpage><lpage>20</lpage><history><date date-type="received" iso-8601-date="2023-02-26"><day>26</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО «Бионика Медиа»</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/288340">https://journals.eco-vector.com/2073-4034/article/view/288340</self-uri><abstract xml:lang="en"><p>Osteoporosis after stroke is not only a medical, but also a significant socially problem. Additional fracture risk of bearing parts of the skeleton, particularly the proximal femur is associated with severe disability, high mortality of patients and a heavy financial burden for the national health system. The article highlights the pathogenic mechanisms of bone metabolism disorders, developing after stroke. The article demonstrates the role of the endocrine system, nutritive factors, degree of immobilization and concomitant drug therapy in the development of osteoporosis. We discuss the possible non-drug methods and medicines for the treatment of these patients.</p></abstract><trans-abstract xml:lang="ru"><p>Остеопороз при инсульте является не только медицинской, но и социально значимой проблемой. Дополнительный риск переломов опорных частей скелета, особенно проксимальных отделов бедра, ассоциируется с тяжелой инвалидизацией больных, высокой смертностью пациентов и тяжелым финансовым бременем для национальной системы здравоохранения. В статье освещены патогенетические механизмы развития нарушений костного обмена после инсульта. Показана роль эндокринных, нутритивных факторов, а также иммобилизации и характера лекарственной терапии в развитии остеопороза. Обсуждаются возможные немедикаментозные методы и лекарственные средства для лечения данной группы пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>osteoporosis</kwd><kwd>bisphosphonates</kwd><kwd>vitamin D</kwd><kwd>calcium</kwd><kwd>fractures</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>остеопороз</kwd><kwd>бисфосфонаты</kwd><kwd>витамин D</kwd><kwd>кальций</kwd><kwd>переломы</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Beaupre G.S., Lew H.L. Bone-density changes after stroke. Am. J. Phys. Med. Rehabil. 2006; 85(5): 464- 72.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hamdy R.C., Moore S.W., Cancellaro V.A., Harvill L.M. 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