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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">288602</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">PREVALENCE AND PRINCIPLES OF MANAGEMENT OF PATIENTS WITH BARRETT'S ESOPHAGUS</article-title><trans-title-group xml:lang="ru"><trans-title>РАСПРОСТРАНЕННОСТЬ И ПРИНЦИПЫ ВЕДЕНИЯ ПАЦИЕНТОВ С ПИЩЕВОДОМ БАРРЕТТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tsukanov</surname><given-names>V. V</given-names></name><name xml:lang="ru"><surname>Цуканов</surname><given-names>В. В</given-names></name></name-alternatives><bio xml:lang="en"><p>MD, Prof., Head of the Clinical Department of Pathology of the Digestive System in Adults</p></bio><bio xml:lang="ru"><p>д.м.н., проф. зав. клиническим отделением патологии пищеварительной системы у взрослых</p></bio><email>gastro@impn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kasparov</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Каспаров</surname><given-names>Э. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasyutin</surname><given-names>A. V</given-names></name><name xml:lang="ru"><surname>Васютин</surname><given-names>А. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Onuchina</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Онучина</surname><given-names>Е. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tonkikh</surname><given-names>Yu. L</given-names></name><name xml:lang="ru"><surname>Тонких</surname><given-names>Ю. Л</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Butorin</surname><given-names>N. N</given-names></name><name xml:lang="ru"><surname>Буторин</surname><given-names>Н. Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FSBIS «Scientific Research Institute of Medical Problems of the North»</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Научно-исследовательский институт медицинских проблем Севера»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">SBEIFPE “Irkutsk State Medical Academy of Postgraduate Education» of RMPH</institution></aff><aff><institution xml:lang="ru">ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РФ</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">FSBEI HPE “Khakassia State University n.a. N.F. Katanov"</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВПО «Хакасский государственный университет им. Н.Ф. Катанова»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-01-20" publication-format="electronic"><day>20</day><month>01</month><year>2016</year></pub-date><volume>23</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2016)</issue-title><issue-title xml:lang="ru">№2 (2016)</issue-title><fpage>28</fpage><lpage>30</lpage><history><date date-type="received" iso-8601-date="2023-02-26"><day>26</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ООО «Бионика Медиа»</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/288602">https://journals.eco-vector.com/2073-4034/article/view/288602</self-uri><abstract xml:lang="en"><p>The article analyzes data on the prevalence and principles of management of patients with Barrett's esophagus. The prevalence of Barrett's esophagus among Caucasians in Siberia varies around 1.5-2.1%. Currently, the leading treatments for Barrett's esophagus include radiofrequency ablation and long-term use of proton pump inhibitors. The chemotherapeutic effect is achieved by the use of aspirin, nonsteroidal anti-inflammatory drugs and ursodeoxycholic acid.</p></abstract><trans-abstract xml:lang="ru"><p>В статье проанализированы сведения о распространенности и принципах ведения пациентов с пищеводом Барретта. Распространенность пищевода Барретта среди представителей европеоидной расы Сибири колеблется на уровне 1,5-2,1%. К ведущим методам лечения пищевода Барретта в настоящее время относятся радиочастотная аблация и длительное применение ингибиторов протонной помпы. Химиотерапевтический эффект достигается при применении аспирина, нестероидных противовоспалительных средств и урсодезоксихолевой кислоты.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Barretts esophagus</kwd><kwd>esophageal cancer</kwd><kwd>esophageal epithelial dysplasia</kwd><kwd>proton pump inhibitors</kwd><kwd>ursodeoxycholic acid</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пищевод Барретта</kwd><kwd>рак пищевода</kwd><kwd>дисплазия эпителия пищевода</kwd><kwd>ингибиторы протонной помпы</kwd><kwd>урсодезоксихолевая кислота</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Spechler S.J., Sharma P., Souza R.F., et al. American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology. 2011;140(3):1084-91.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Wang K.K., Sampliner R.E. 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