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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">288727</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">DIAGNOSIS AND TREATMENT OF ASPIRATION SYNDROME IN INFANTS</article-title><trans-title-group xml:lang="ru"><trans-title>Диагностика и лечение аспирационного синдрома у детей раннего возраста</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rogova</surname><given-names>O. A</given-names></name><name xml:lang="ru"><surname>Рогова</surname><given-names>О. А</given-names></name></name-alternatives><bio xml:lang="en"><p>Postgraduate Student at the Department of Clinical Diagnostics and Rehabilitation Treatment</p></bio><bio xml:lang="ru"><p>клинический аспирант отделения диагностики и восстановительного лечения</p></bio><email>mohna4a@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bakradze</surname><given-names>M. D</given-names></name><name xml:lang="ru"><surname>Бакрадзе</surname><given-names>М. Д</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kuzenkova</surname><given-names>L. M</given-names></name><name xml:lang="ru"><surname>Кузенкова</surname><given-names>Л. М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Uvakina</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Увакина</surname><given-names>Е. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kazakova</surname><given-names>K. A</given-names></name><name xml:lang="ru"><surname>Казакова</surname><given-names>К. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FSBI Scientific Center for Children's Health of RMPH</institution></aff><aff><institution xml:lang="ru">ФГБУ «Научный центр здоровья детей» МЗ РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-02-20" publication-format="electronic"><day>20</day><month>02</month><year>2016</year></pub-date><volume>23</volume><issue>4</issue><issue-title xml:lang="en">NO4 (2016)</issue-title><issue-title xml:lang="ru">№4 (2016)</issue-title><fpage>56</fpage><lpage>61</lpage><history><date date-type="received" iso-8601-date="2023-02-26"><day>26</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ООО «Бионика Медиа»</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/288727">https://journals.eco-vector.com/2073-4034/article/view/288727</self-uri><abstract xml:lang="en"><p>Objective: to study the frequency of aspiration processes in children admitted with respiratory complaints; to evaluate the effectiveness of different treatments of microaspiration syndrome. Methods: for detecting the frequency of aspiration syndrome in infants and young children with acute lower respiratory tract lesions without neurological disorders, monitoring of 162 children in the period 2013-2015 was conducted. The comparison group consisted of 24 children with aspiration on the background of an organic lesion of the central nervous system. Results: Of 162 children surveyed, signs of aspiration were revealed in 27 cases, accounting for 16.7%. Aspiration syndrome incidence was highest in the first six months of life; of the 67 children admitted to hospital with acute lower respiratory tract lesions without concomitant neurologic disease before the age of 6 months, aspiration was detected in 17 cases (25%). Gastroesophageal reflux (GER) occurred in 4 children in the first six months of life, which was not different from the frequency of GER in healthy children. Of 88 children in the latter six months, only 3 children had signs of microaspiration (3.5%). Of the 47 neurologically healthy children, recurrent symptoms of broncho-pulmonary diseases were observed in 20 children. Conclusion: These data show that the food microaspiration is sufficiently frequent cause of respiratory syndrome, especially among infants. Respiratory syndrome in children with the food microaspiration syndrome is characterized by repeated episodes of cough, obstruction with a trend towards prolonged duration due to the continuing aspiration.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования: изучить частоту аспирационных процессов у детей, госпитализированных с респираторными жалобами, оценить эффективность различных методов лечения микроаспирационного синдрома. Методы: для выявления частоты аспирационного синдрома у детей грудного и раннего возраста с острым поражением нижних дыхательных путей без неврологической патологии проведено наблюдение за 162 детьми в 2013-2015 гг. В группу сравнения вошли 24 ребенка с аспирацией на фоне органического поражения центральной нервной системы. Результаты: из 162 обследованных детей признаки аспирации выявлены в 27 случаях, что составило 16,7%. Частота аспирационного синдрома была наибольшей в первом полугодии жизни: из 67 детей, госпитализированных в клинику с острым поражением нижних дыхательных путей без сопутствующей неврологической патологии в возрасте до 6 месяцев, аспирация выявлена в 17 (25%) случаях. Гастроэзофагеальный рефлюкс (ГЭР) имел место у 4 детей 1-го полугодия жизни, что не отличается от частоты ГЭР у здоровых детей. Во 2-м полугодии жизни из 88 детей лишь 3 ребенка были с признаками микроаспирации (3,5%). Из 47 неврологически здоровых детей у 20 наблюдались рецидивирующие симптомы заболеваний бронхо-легочной системы. Заключение: приведенные данные показывают, что микроаспирация пищи является достаточно частой причиной респираторного синдрома, прежде всего у детей первого года жизни. Респираторный синдром у детей с синдромом микроаспирации пищи характеризуется повторными эпизодами кашля, обструкции с тенденцией к затяжному течению за счет продолжающейся аспирации.</p></trans-abstract><kwd-group xml:lang="en"><kwd>dysphagia</kwd><kwd>aspiration</kwd><kwd>Sandifer's syndrome</kwd><kwd>infants</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>дисфагия</kwd><kwd>аспирация</kwd><kwd>синдром Сандифера</kwd><kwd>дети раннего возраста</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Cecilia P.M., Callahan С. Aspiration Syndromes. Medscape. 2014. URL: http://emedicine.med-scape.com/article/1005303-overview (available: 21.08.2014).</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Sacre L., Vandenplas Y. Gastroesophageal reflux associated with respiratory abnormalities during sleep. J. Pediatr. Gastroenterol. 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