PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media289220ArticlesСтатьиResearch ArticlePOTENTIALS FOR THE USE OF URSODEOXYCHOLIC ACID IN THE THERAPY OF INTRAHEPATIC CHOLESTASIS OF PREGNANCYВозможности применения урсодезоксихолевой кислоты в рамках терапии внутрипеченочного холестаза беременныхGulenchenkoYu. SГуленченкоЮ. СPartsvania-VinogradovaE. VПарцваниа-ВиноградоваЕ. В

therapists at the Branch; resident physician at the Department of Propedeutics of Internal Diseases and Gastroenterology

врач-терапевт филиала; ординатор кафедры пропедевтики внутренних болезней и гастроэнтерологии

katrin3108@mail.ruDichevaD. TДичеваД. ТAndreevD. NАндреевД. НZaborovskiyA. VЗаборовскийА. ВTararinaL. AТараринаЛ. АFBHCISCH MIA of RussiaФКУЗ ГКГ МВД РоссииBranch Branch SBHCI CP №115 MHCD CP № 79Филиал ГБУЗ ГП № 115 ДЗМ ГП № 79SBEI HPE "Moscow State Medical Stomatological University n.a. A.I. Evdokimov" of RMHГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава РФ100820162315NO15 (2016)№15 (2016)545726022023Copyright ©; 2016, Bionika MediaCopyright ©; 2016, ООО «Бионика Медиа»2016Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/289220

According to modern concepts, intrahepatic cholestasis of pregnancy (IHCP) is a cholestatic liver disease that develops in II and III trimesters of pregnancy, and characterized by itching and increased concentration of bile acids in the blood serum. Currently, ursodeoxycholic acid is considered as the drug of choice for the treatment of IHCP as defined by substantial evidence of efficacy and safety of the drug within the treatment of this pathology.

По современным представлениям, внутрипеченочный холестаз беременных (ВХБ) представляет собой холестатическое заболевание печени, развивающееся во II или III триместре беременности, характеризующееся зудом и повышением концентрации желчных кислот в сыворотке крови. В настоящее время урсодезоксихолевая кислота считается препаратом выбора для лечения ВХБ, что определено существенной доказательной базой эффективности и безопасности данного препарата в рамках терапии рассматриваемой патологии.

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