PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media289755ArticlesСтатьиResearch ArticleThe use of Lactobacillus rhamnosus GG-containing probiotics for the prevention of atopic dermatitis in childrenПрименение пробиотиков с Lactobacillus rhamnosus GG в профилактике атопического дерматита у детейMonakhovK. NМонаховК. Н

MD, Prof. Department of Dermatovenereology with the Clinic

д.м.н., проф. кафедры дерматовенерологии с клиникой

knmonakhov@mail.ruDombrovskayaD. KДомбровскаяД. К

Department of Family Medicine

Кафедра семейной медицины

NazarenkoE. VНазаренкоЭ. В

Department of Dermatovenereology with the Clinic

Кафедра дерматовенерологии с клиникой

First St. Petersburg Medical University n.a. Acad. I.P. PavlovПервый Санкт-Петербургский медицинский университет им. акад. И.П. Павлова10012017241NO1 (2017)№1 (2017)616526022023Copyright ©; 2017, Bionika MediaCopyright ©; 2017, ООО «Бионика Медиа»2017Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/289755

There are qualitative and quantitative differences in the composition of the intestinal microflora in healthy infants and in children with atopic dermatitis. These data gave an impulse to development of concept that the beneficial bacteria in the intestinal microflora, called probiotics, can restore intestinal homeostasis and prevent allergies or decrease its manifestation through interaction with the immune cells in the intestine. Not all probiotic strains have the same properties. The article summarizes the current understanding of the possibilities of prevention of atopic dermatitis in children using Lactobacillus rhamnosus GG. A review of research on the prevention of atopic dermatitis in children in the prenatal and postnatal periods is presented.

Существуют качественные и количественные различия в составе кишечной микрофлоры у здоровых грудных детей и у больных атопическим дерматитом. Эти данные послужили толчком для появления концепции о том, что полезные бактерии в составе кишечной микрофлоры человека, названные пробиотиками, могут восстанавливать кишечный гомеостаз и предотвращать возникновение аллергии или уменьшать ее проявления отчасти за счет взаимодействия с иммунными клетками в кишечнике. Не все штаммы пробиотиков обладают одинаковыми свойствами. В статье обобщены современные представления о возможностях профилактики атопического дерматита у детей при помощи Lactobacillus rhamnosus GG. Представлен обзор исследований по профилактике атопического дерматита у детей в пренатальном и постнатальном периодах.

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