<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">294340</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">BARRETT'S ESOPHAGUS WITH LOW-GRADE DYSPLASIA: A NEW LOOK AT THE PROBLEM</article-title><trans-title-group xml:lang="ru"><trans-title>Пищевод Барретта с дисплазией низкой степени: новый взгляд на проблему</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bakulin</surname><given-names>I. G</given-names></name><name xml:lang="ru"><surname>Бакулин</surname><given-names>И. Г</given-names></name></name-alternatives><bio xml:lang="en"><p>MD, Prof., Head of the Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietology</p></bio><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии</p></bio><email>igbakulin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belousova</surname><given-names>L. N</given-names></name><name xml:lang="ru"><surname>Белоусова</surname><given-names>Л. Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FSBEI HE NWSMU n.a. I.I. Mechnikov of RMH</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО СЗГМУ им. И.И. Мечникова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2017</year></pub-date><volume>24</volume><issue>5S</issue><issue-title xml:lang="en">NOS5 (2017)</issue-title><issue-title xml:lang="ru">№S5 (2017)</issue-title><fpage>44</fpage><lpage>46</lpage><history><date date-type="received" iso-8601-date="2023-02-27"><day>27</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО «Бионика Медиа»</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/294340">https://journals.eco-vector.com/2073-4034/article/view/294340</self-uri><abstract xml:lang="en"><p>The article provides an overview of modern approaches to the management of patients with Barrett’s esophagus and various stages of the neoplastic process against its background. The new recommendations on the diagnosis and treatment of Barrett’s esophagus with low-grade dysplasia and the algorithm for carrying out these measures proposed in 2017 were analyzed. In case of confirmation of the above mentioned diagnosis with repeated endoscopic examination (the presence of dysplasia should be confirmed by at least two pathomorphologists, preferably from different institutions), an endoscopic ablation, preferably a radiofrequency ablation, or follow-up, is indicated.</p></abstract><trans-abstract xml:lang="ru"><p>В статье приводится обзор современных подходов к ведению пациентов с пищеводом Барретта и различными стадиями неопластического процесса на его фоне. Проанализированы предложенные в 2017 г. новые рекомендации по диагностике и лечению пищевода Барретта с дисплазией низкой степени и алгоритм такого проведения этих мероприятий. В случае подтверждения вышеуказанного диагноза при повторном эндоскопическом исследовании (наличие дисплазии должно быть подтверждено как минимум двумя патоморфологами, предпочтительно из разных учреждений) показано проведение эндоскопической абляции, предпочтительно радиочастотной, или продолжение наблюдения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Barrett's esophagus</kwd><kwd>low-grade dysplasia</kwd><kwd>esophageal cancer</kwd><kwd>radiofrequency ablation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пищевод Барретта</kwd><kwd>дисплазия низкой степени</kwd><kwd>рак пищевода</kwd><kwd>радиочастотная абляция</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>El-Serag H.B., Sweet S., Winchester C.C., Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63:871-80.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hur C., Miller M., Kong C.Y., Dowling, E.C., Nattinger, K.J., Dunn M., Feuer, E.J. Trends in esophageal adenocarcinoma incidence and mortality. Cancer. 2013;119:1149-58.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Spechler S.J., Sharma P., Souza R.F., Inadomi J.M., Shaheen N.J. American Gastroenterological Association medical positionstatement on the management of Barrett's esophagus. Gastroenterology. 2011;140(3):1084-91.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Fitzgerald R.C., di Pietro M., Ragunath K., Ang Y., Kang J.Y., Watson P., Trudgill N., British Society of Gastroenterology. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus. Gut. 2014;63(1):7-42.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Shaheen N.J., Falk G.W., Iyer P.G., Gerson L. Diagnosis and Management of Barrett's Esophagus. Am. J. Gastroenterol. 2016;111:30-50.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>di Pietro M., Fitzgerald R.C. Revised British Society of Gastroenterology recommendation on the diagnosis and management of Barrett's oesophagus with low-grade dysplasia. Gut. Published Online First: 07 April 2017. Doi: 10.1136/gutjnl-2017-314135.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>http://www.gastro.ru/userfiles/R_Barret_ 14.pdf</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Duits L.C., Phoa K.N., Curvers W.L., et al. Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel. Gut. 2015;64:700-6.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Singh S., Manickam P., Amin A.V., Samala N., Schouten L.J., Iyer P.G., Desai T.K. Incidence of esophageal adenocarcinoma in Barrett's esophagus with low-grade dysplasia: a systematic review and metaanalysis. Gastrointest. Endosc. 2014;79: 897-909.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Phoa K.N., Van Vilsteren F.G., Weusten B.L., et al. Radiofrequency ablation vs endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia: a randomized clinical trial. JAMA 2014;311:1209-17.</mixed-citation></ref></ref-list></back></article>
