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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">294368</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">IS THROMBOCYTOPENIA ALWAYS THE PROBLEM OF THE HEMATOLOGIST? DIAGNOSTIC AND THERAPEUTIC ALGORITHMS IN PRACTICE OF THERAPIST AND GASTROENTEROLOGIST</article-title><trans-title-group xml:lang="ru"><trans-title>Всегда ли тромбоцитопения - проблема гематолога? Лечебно-диагностические алгоритмы в практике терапевта и гастроэнтеролога</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bakulin</surname><given-names>I. G</given-names></name><name xml:lang="ru"><surname>Бакулин</surname><given-names>И. Г</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belousova</surname><given-names>L. N</given-names></name><name xml:lang="ru"><surname>Белоусова</surname><given-names>Л. Н</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietology</p></bio><bio xml:lang="ru"><p>к.м.н., кафедра пропедевтики внутренних болезней, гастроэнтерологии и диетологии</p></bio><email>liya-belousova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Evdokimova</surname><given-names>L. S</given-names></name><name xml:lang="ru"><surname>Евдокимова</surname><given-names>Л. С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FSBEI HE “NWSMU n.a. I.I. Mechnikov" of RMH</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «СЗГМУ им. И.И. Мечникова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2017</year></pub-date><volume>24</volume><issue>5S</issue><issue-title xml:lang="en">NOS5 (2017)</issue-title><issue-title xml:lang="ru">№S5 (2017)</issue-title><fpage>78</fpage><lpage>84</lpage><history><date date-type="received" iso-8601-date="2023-02-27"><day>27</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО «Бионика Медиа»</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/294368">https://journals.eco-vector.com/2073-4034/article/view/294368</self-uri><abstract xml:lang="en"><p>In recent years, sufficient evidence has been obtained on the development of thrombocytopenia in various pathological conditions, which indicates the need for knowledge and experience of doctors of various clinical specialties in the therapeutic and diagnostic activities. The article considers the mechanisms of thrombocytopenia development. The clinical algorithm and laboratory and instrumental methods of examination allowing to elucidate the genesis of thrombocytopenia are discussed. Particular attention is paid to the mechanisms of thrombocytopenia development in gastrointestinal diseases.</p></abstract><trans-abstract xml:lang="ru"><p>За последние годы получено достаточно доказательных данных о развитии тромбоцитопении при различных патологических состояниях, что указывает на необходимость знаний и опыта врачей различных клинических специальностей при проведении лечебно-диагностических мероприятий. В статье рассматриваются механизмы развития тромбоцитопении. Приводятся клинический алгоритм и лабораторно-инструментальные методы исследования, позволяющие выяснять генез тромбоцитопении. Особое внимание уделяется механизмам развития тромбоцитопении при заболеваниях пищеварительной системы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Helicobacter pylori</kwd><kwd>thrombocytopenia</kwd><kwd>Helicobacter pylori</kwd><kwd>hepatitis C virus</kwd><kwd>hepatic cirrhosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>тромбоцитопения</kwd><kwd>вирус гепатита С</kwd><kwd>цирроз печени</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Provan D., Stasi R., Newland A.S., Blanchette V.S., Bolton-Maggs P., Bussel J.B., et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168-86.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Бакулин И.Г., Шарабанов А.С., Моляренко Е.В., Яковлева Е.В. Тромбоцитопении у больных хроническим гепатитом С. 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