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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">296989</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2019.3.20-26</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Neurorehabilitation predicated on the principles of evidence-based medicine: Austrian recommendations for the rehabilitation of post-stroke patients</article-title><trans-title-group xml:lang="ru"><trans-title>Нейрореабилитация, основанная на принципах доказательной медицины: австрийские рекомендации по реабилитации больных после инсульта</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bushkova</surname><given-names>Yulia V.</given-names></name><name xml:lang="ru"><surname>Бушкова</surname><given-names>Ю. В</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, Senior Reseracher, Physical Therapy Physician</p></bio><bio xml:lang="ru"><p>к.п.н., старший науч. сотр., врач лечебной физкультуры</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Research Institute of Cerebrovascular Pathology and Stroke, Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">НИИ цереброваскулярной патологии и инсульта, РНИМУ им. Н.И. Пирогова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2019</year></pub-date><volume>26</volume><issue>3</issue><issue-title xml:lang="en">VOL 26, NO3 (2019)</issue-title><issue-title xml:lang="ru">ТОМ 26, №3 (2019)</issue-title><fpage>20</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2023-02-28"><day>28</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, ООО «Бионика Медиа»</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/296989">https://journals.eco-vector.com/2073-4034/article/view/296989</self-uri><abstract xml:lang="en"><p>Modern neurorehabilitation, based on the principles of evidence-based medicine, makes us move away from the GRADE-concept (model of successive rehabilitation). There were grounds for the beginning of rehabilitation in the emergency room in the first 24-48 hours. Proper organization of the stroke compartment reduces mortality and disability. Prerequisites are the presence of a rehabilitation team (level A), whose members are: a neurologist, a physiotherapist, an ergotherapist, a speech therapist, as well as a psychologist and a social worker; regular consultations with leading neurologists and other doctors to determine and document the therapy, its dynamics; cognitive screening; discussion of the results of the examination and treatment plan with relatives. Rehabilitation activities are based on the use of the International Classification of Functioning, Vital Activity and Health (ICF) and are performed at structural and functional levels (for example, muscle strength, tone, breathing), differ in goals, types of activity, patient participation and should be easily measured and painted time, to enable the patient to be motivated, as well as to be relevant to his condition (level A). On the other hand, the rehabilitation assessment at the early stages may also have predictive value (the Bartel index is within 5 days), based on the use of standard scales. The use of various therapeutic techniques that have a level of evidence of IA-III is performed in various combinations in each individual patient, depending on the existing pathological syndromes. There is evidence of the positive effects of levodopa and selective serotonin reuptake inhibitors (class II - III, level B - C), as well as specific peptide complexes - Cerebrolysin at a dose of 30 ml in a course of 3 weeks or more (class II, level B). Rehabilitation in the long term can be carried out at home, even a year after a stroke, balance exercises, gait training using different methods, training for the upper limbs are effective (grade B) and contribute to the reduction of disability.</p></abstract><trans-abstract xml:lang="ru"><p>Современная нейрореабилитация, базирующаяся на принципах доказательной медицины, заставляет уйти от GRADE-концепции (модель преемственной реабилитации). Появились основания для начала реабилитации в отделении неотложной терапии в первые 24-48 часов. Правильная организация инсультного отделения позволяет снизить смертность и инвалидизацию. Обязательным условием служит наличие реабилитационной команды (уровень А), членами которой являются невролог, физиотерапевт, эрготерапевт, логопед, а также психолог и социальный работник; регулярные консилиумы с ведущими неврологами и другими врачами для определения и документирования терапии, ее динамики; когнитивный скрининг; обсуждение результатов обследования и плана лечения с родственниками. Реабилитационные мероприятия базируются на применении Международной классификации функционирования, жизнедеятельности и здоровья (МФК) и выполняются на структурном и функциональном уровнях (например, мышечная сила, тонус, дыхание), различаются по целям, видам активности, участию больного и должны быть легкоизмеряемыми и расписаны во времени для возможности мотивации пациента, а также быть релевантными его состоянию (уровень A). С другой стороны, реабилитационная оценка на ранних этапах может иметь и прогностическое значение (индекс Бартел - в течение 5 дней), базирующаяся на применении стандартных шкал. Применение различных терапевтических методик, имеющих уровень доказательности IA-III, выполняется в различных комбинациях в отношении каждого конкретного пациента в зависимости от имеющихся патологических синдромов. Есть данные о положительном влиянии леводопы и селективных ингибиторов обратного захвата серотонина (класс II-III, уровень В-С), а также специфических пептидных комплексов - Церебролизина в дозе 30 мл курсом 3 недели и более (класс II, уровень В). Реабилитация в долгосрочном периоде может проводиться в домашних условиях, даже спустя год после инсульта упражнения на равновесие, обучение походке с использованием разных методов, тренировки для верхних конечностей эффективны (уровень В) и способствуют снижению инвалидности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>comprehensive rehabilitation</kwd><kwd>clinical recommendations for stroke</kwd><kwd>early rehabilitation</kwd><kwd>outpatient rehabilitation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>комплексная реабилитация</kwd><kwd>клинические рекомендации при инсульте</kwd><kwd>ранняя реабилитация</kwd><kwd>амбулаторная реабилитация</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>United Nations Organisation. https://www.un.org/ development/desa/disabilities/convention-on-the-rights-of-persons-with-disabilities/artide-26-habiiitation-and- rehabiiitation.htmi. 201</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Neuhaus A.A., Couch Y., Hadiey G., Buchan A.M. 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