PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media29767310.18565/pharmateca.2019.5.127-132ArticlesСтатьиResearch ArticleCough in womenКашель у женщинKlyachkinaIrina L.КлячкинаИ. Л

PhD, Associate Professor at the Department of Pulmonology

к.м.н., доцент кафедры пульмонологии

formozailk2012@yandex.ruRussian Medical Academy of Continuous Professional EducationРоссийская медицинская академия последипломного образования15052019265VOL 26, NO5 (2019)ТОМ 26, №5 (2019)12713228022023Copyright ©; 2019, Bionika MediaCopyright ©; 2019, ООО «Бионика Медиа»2019Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/297673

A description of the pathogenesis of chronic cough (CC) in women is presented. Gender and age differences in the prevalence of CC and the sensitivity of the cough receptors are shown. The role of the female sex hormones and their effect on the cough receptors in the pathogenesis of CC is formulated. Based on the data obtained, the pathogenetic concept of CC as an independent disease is defined. Considering the difficulties of using antitussive drugs with their limited focus on either central mechanisms or peripheral receptors, such drug as Rengalin is considered, which combines antitussive, anti-inflammatory and bronchodilatory actions with the possibility of effective treatment of any type of cough in acute and chronic infectious and inflammatory allergic diseases.

Приводится описание патогенеза хронического кашля (ХК) у женщин. Показаны гендерные и возрастные различия в распространенности ХК и чувствительности рецепторов кашлевого рефлекса. Сформулированы роль половых женских гормонов и их влияние на рецепторы кашлевого рефлекса в патогенезе ХК. На основе полученных данных сформулирована патогенетическая концепция ХК как самостоятельного заболевания. С учетом сложностей применения противокашлевых препаратов с их ограниченной направленностью либо на центральные механизмы, либо на периферические рецепторы рассматривается такой препарат, как Ренгалин, сочетающий противокашлевое, противовоспалительное и бронхолитическое действия с возможностью применения для эффективной терапии любого вида кашля при острых и хронических инфекционно-воспалительных и аллергических заболеваниях.

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