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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">313158</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2021.6.14-18</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Endometriosis in children and adolescents</article-title><trans-title-group xml:lang="ru"><trans-title>Эндометриоз у детей и подростков</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Artymuk</surname><given-names>N. V</given-names></name><name xml:lang="ru"><surname>Артымук</surname><given-names>Н. В</given-names></name></name-alternatives><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology n.a. Prof. G.A. Ushakova</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой акушерства и гинекологии им. проф. Г.А. Ушаковой</p></bio><email>artymuk@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zotova</surname><given-names>O. A</given-names></name><name xml:lang="ru"><surname>Зотова</surname><given-names>О. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vaulina</surname><given-names>E. N</given-names></name><name xml:lang="ru"><surname>Ваулина</surname><given-names>Е. Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kemerovo State Medical University</institution></aff><aff><institution xml:lang="ru">Кемеровский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kuzbass Clinical Hospital n.a. S.V. Belyaev</institution></aff><aff><institution xml:lang="ru">Кузбасская клиническая больница им. С.В. Беляева</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2021</year></pub-date><volume>28</volume><issue>6</issue><issue-title xml:lang="en">VOL 28, NO6 (2021)</issue-title><issue-title xml:lang="ru">ТОМ 28, №6 (2021)</issue-title><fpage>14</fpage><lpage>18</lpage><history><date date-type="received" iso-8601-date="2023-03-03"><day>03</day><month>03</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО «Бионика Медиа»</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/313158">https://journals.eco-vector.com/2073-4034/article/view/313158</self-uri><abstract xml:lang="en"><p>Edometriosis - insidious and mysterious - has become a real epidemic of the century: it is one of the most common gynecological diseases. There is a need to change the generally accepted views on this problem as an «adult disease» and to search for markers of early diagnosis in girls with the selection of correction methods. An assessment of 50 foreign and domestic literature sources reflecting clinical manifestations, pathogenesis, diagnosis and treatment of endometriosis in children and adolescents was performed. About half of patients of reproductive age report the onset of symptoms of endometriosis during adolescence. However, the difference in clinical manifestations of the course of the disease from adult patients complicates and slows down the process of establishing a diagnosis. It is necessary to develop methods for early diagnosis of endometriosis in female adolescentss in order to prevent its progression and maintain fertility.</p></abstract><trans-abstract xml:lang="ru"><p>Эдометриоз - коварный и загадочный - стал настоящей эпидемией века: это одно из самых распространенных гинекологических заболеваний. Существует необходимость изменения общепринятых взглядов на эту проблему как «взрослой болезни» и поиска маркеров ранней диагностики у девочек с подбором методов коррекции.Проведена оценка 50 зарубежных и отечественных источников литературы, отражающих клинические проявления, патогенез, диагностику и лечение эндометриоза у детей и подростков. Около половины пациенток репродуктивного возраста отмечают появление симптомов эндометриоза в подростковом возрасте. Однако отличие клинических проявлений течения заболевания от взрослых пациенток затрудняет и замедляет процесс установления диагноза. Необходима разработка методик ранней диагностики эндометриоза у девочек-подростков с целью предотвращения его прогрессирования и сохранения фертильности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>endometriosis</kwd><kwd>endometrioma</kwd><kwd>female adolescents</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эндометриоз</kwd><kwd>эндометриома</kwd><kwd>девочки-подростки</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Gaia-Otean A.I., Braicu C., Guiei D., et al. Ovarian endometriosis, a precursor of ovarian cancer: Histological aspects, gene expression and microRNA alterations (Review). Exp Ther Med. 2021;21(3):243. Doi: 10.3892/etm.2021.9674.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hirsch M., Dhiiion-Smith R., Cutner A.S., et ai. The Prevalence of Endometriosis in Adolescents with Pelvic Pain: A Systematic Review. J. Pediatr Adolesc Gynecol. 2020;33(6):623-30. 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