PharmatecaPharmatecaФарматека2073-40342414-9128Bionika Media67985810.18565/pharmateca.2025.2.32-39ReviewsОбзорыReview ArticleLatent autoimmune diabetes in adults: current concepts of risk factors, diagnosis, and therapyЛатентный аутоиммунный диабет у взрослых: современные представления о факторах риска, диагностике и терапииhttps://orcid.org/0000-0001-8317-7765DrukInna V.ДрукИнна Викторовна
Russian Federation

Dr. Sci. (Med.), Associate Professor, Head of the Department of Internal Medicine and Family Medicine of Continuous Professional Education

д.м.н., доцент, зав. кафедрой внутренних болезней и семейной медицины дополнительного профессионального образования

drukinna@yandex.ruhttps://orcid.org/0000-0001-5852-2782SafronovaSvetlana S.СафроноваСветлана Сергеевна
Russian Federation

Assistant Professor, Department of Internal Medicine and Family Medicine of Continuous Professional Education

ассистент кафедры внутренних болезней и семейной медицины дополнительного профессионального образования

safronova.sv77@gmail.comKulebakinaKsenia A.КулебакинаКсения Александровна
Russian Federation

Endocrinologist

врач-эндокринолог

ksenia-114@mail.ruOmsk State Medical UniversityОмский государственный медицинский университетClinical Diagnostic CenterКлинический диагностический центр2003202532232391805202518052025Copyright ©; 2025, Bionika MediaCopyright ©; 2025, ООО «Бионика Медиа»2025Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/2073-4034/article/view/679858

Slowly developing immune related diabetes mellitus of adults (LADA diabetes) is one of the most common types of atypical diabetes. LADA diabetes is a clinically and metabolically hybrid form of type 1 and 2 diabetes mellitus (DM) with a slowly progressive course. Due to its similarity in the early stages in clinical course with DM2 and in pathogenesis – with DM1, it is often overlooked in clinical practice. The article presents current criteria for the diagnosis of latent autoimmune diabetes in adults and describes differentiated tactics for choosing therapy.

Медленно развивающийся иммуноопосредованный сахарный диабет взрослых (LADA-диабет) – один из наиболее распространенных вариантов атипичного диабета. LADA-диабет является клинически и метаболически гибридной формой сахарного диабета (СД) 1 и 2 типов с медленно прогрессирующим течением. Из-за его сходства на ранних стадиях по клиническому течению с СД2 и по патогенезу – с СД1 часто упускается из виду в клинической практике. В статье приведены современные критерии диагностики латентного аутоиммунного диабета у взрослых и описана дифференцированная тактика выбора терапии.

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