<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">691252</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2025.5.32-40</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Modern strategy for managing patients with follicular occlusion syndrome</article-title><trans-title-group xml:lang="ru"><trans-title>Современная стратегия ведения пациентов с синдромом фолликулярной окклюзии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6890-2041</contrib-id><name-alternatives><name xml:lang="en"><surname>Botkina</surname><given-names>Aleksandra S.</given-names></name><name xml:lang="ru"><surname>Боткина</surname><given-names>Александра Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Ned.), Associate Professor, Department of Hospital Pediatrics named after Academician V.A. Tabolin, Pediatric Faculty</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры госпитальной педиатрии им. акад. В.А. Таболина педиатрического факультета</p></bio><email>botkina@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8097-2816</contrib-id><name-alternatives><name xml:lang="en"><surname>Gumennaya</surname><given-names>E. R.</given-names></name><name xml:lang="ru"><surname>Гуменная</surname><given-names>Э. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>botkina@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-2656-3278</contrib-id><name-alternatives><name xml:lang="en"><surname>Tyukhaeva</surname><given-names>O. Yu.</given-names></name><name xml:lang="ru"><surname>Тюхаева</surname><given-names>О. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>botkina@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Children’s Clinical Hospital – Branch of Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российская детская клиническая больница – филиал ФГАОУ ВО РНИМУ им. Н.И. Пирогова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-09-24" publication-format="electronic"><day>24</day><month>09</month><year>2025</year></pub-date><volume>32</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>32</fpage><lpage>40</lpage><history><date date-type="received" iso-8601-date="2025-09-23"><day>23</day><month>09</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-09-23"><day>23</day><month>09</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ООО «Бионика Медиа»</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/691252">https://journals.eco-vector.com/2073-4034/article/view/691252</self-uri><abstract xml:lang="en"><p>Follicular occlusion syndrome is a chronic inflammatory skin disease that includes hidradenitis suppurativa, acne conglobata, abscessed disruptive folliculitis, Hoffman’s perifolliculitis, epithelial coccygeal passage. The disease has a chronic, continuously relapsing course and has a serious impact on the patient’s quality of life. Early diagnosis and treatment can effectively slow down the progression of the disease, prevent the formation of disfiguring scars, reduce the pathological impact of the disease on the somatic and mental health of patients, and reduce the economic burden. Currently, there is no consensus on the treatment of follicular occlusion syndrome. The article highlights and discusses existing approaches to the treatment of this complex category of patients in the world.</p></abstract><trans-abstract xml:lang="ru"><p>Синдром фолликулярной окклюзии представляет собой хроническое воспалительное заболевание кожи, включающее гнойный гидраденит, конглобатные акне, абсцедирующий и подрывающий фолликулит и перифолликулит Гоффмана, эпителиальный копчиковый ход. Заболевание имеет хроническое непрерывно-рецидивирующее течение и оказывает серьезное влияние на качество жизни пациента. Ранняя диагностика и лечение могут эффективно сдерживать прогрессирование заболевания, предотвращать формирование обезображивающих рубцов, уменьшать патологическое влияние заболевания на соматическое и психическое здоровье пациентов, а также снижать экономическое бремя. В настоящее время нет единого консенсуса относительно терапии синдрома фолликулярной окклюзии. В статье освещаются и обсуждаются существующие в мире подходы к терапии этой сложной категории пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>follicular occlusion syndrome</kwd><kwd>acne conglobate</kwd><kwd>hidradenitis suppurativa</kwd><kwd>abscessed disruptive folliculitis</kwd><kwd>Hoffman’s perifolliculitis</kwd><kwd>epithelial coccygeal passage</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром фолликулярной окклюзии</kwd><kwd>акне конглобатные</kwd><kwd>гнойный гидраденит</kwd><kwd>абсцедирующий и подрывающий фолликулит и перифолликулит Гоффмана</kwd><kwd>эпителиальный копчиковый ход</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Zouboulis C.C., Bechara F.G., Fritz K., et al. S2k guideline for the treatment of hidradenitis suppurativa/acne inversa – Short version. J Dtsch Dermatol Ges. 2024;22(6):868–89. https://dx.doi.org/10.1111/ddg.15412</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Federico A., Rossi A., Caro G., et al. Are dissecting cellulitis and hidradenitis suppurativa different diseases? Clin Dermatol. 2021;39(3):496–9. https://dx.doi.org/10.1016/j.clindermatol.2021.01.002</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Pillsbury D.M., Shelley W.B. Dermatology. Annu Rev Med. 1954;5:363–88. https://dx.doi.org/10.1146/annurev.me.05.020154.002051</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Plewig G., Kligman A.M. Acne. Morphogenesis and Treatment. Berlin: Springer. 1975. Р. 192–3.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Plewig G., Steger M. Acne inversa (alias acne triad, acne tetrad or hidradenitis suppurativa). In: Marks R, Plewig G, editors. Acne and Related Disorders. London: Martin Dunitz. 1989. Р. 345–57.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Sabat R., Jemec G.B.E., Matusia., et al. Hidradenitis suppurativa. Nat Rev Dis Primers. 2020;6(1):18. https://dx.doi.org/10.1038/s41572-020-0149-1</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Sung K.Y., Lee S., Jeong Y., Lee S.Y. Dissecting cellulitis of the scalp: A diagnostic challenge. Arch Plast Surg. 2020;47(6):631–2. https://dx.doi.org/10.5999/aps.2020.00633</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Gulliver W., Zouboulis C.C., Prens E., et al. Evidence-based approach to the treatment of hidradenitis suppurativa/acne inversa, based on the European guidelines for hidradenitis suppurativa. Rev Endocr Metab Disord. 2016;17(3):343–51. https://dx.doi.org/10.1007/s11154-016-9328-5</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Chu Y.L., Yu S. Hidradenitis Suppurativa: An Understanding of Genetic Factors and Treatment. Biomedicines. 2024;12(2):338. https://dx.doi.org/10.3390/biomedicines12020338</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Frew J.W. Intrinsic factors in the pathogenesis of hidradenitis suppurativa: Genetics, hormones, and the microbiome. J Am Acad Dermatol. 2024;91(6S):S12–6. https://dx.doi.org/10.1016/j.jaad.2024.08.052</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Nikolakis G., Kokolakis G., Kaleta K., et al. Pathogenese der Hidradenitis suppurativa/Acne inversa [Pathogenesis of hidradenitis suppurativa/acne inversa]. Hautarzt. 2021;72(8):658–65. German. https://dx.doi.org/10.1007/s00105-021-04853-x</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Wang Z., Yan Y., Wang B. Secretase Genetics of Hidradenitis Suppurativa: A Systematic Literature Review. Dermatology. 2021;237(5):698–704. https://dx.doi.org/10.1159/000512455</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Verma S.S., Sharma K., Chhabra S. Pathogenesis of Hidradenitis Suppurativa: An Immunological Perspective. Indian J Dermatol. 2023;68(3):296–300. https://dx.doi.org/10.4103/ijd.ijd_594_22</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Jastrz B., Szepietowski J.C., Matusiak Ł. Hidradenitis suppurativa and follicular occlusion syndrome: Where is the pathogenetic link? Clin Dermatol. 2023;41(5):576–83. https://dx.doi.org/10.1016/j.clindermatol.2023.08.021</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Frew J.W., Hawkes J.E., Krueger J.G. Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms. Ther Adv Chronic Dis. 2019;10:2040622319830646. https://dx.doi.org/10.1177/2040622319830646</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Ceruti J.M., Leirs G.J., Balana M.E. Androgens and androgen receptor action in skin and hair follicles. Mol Cell Endocrinol. 2018;465:122–33. https://dx.doi.org/10.1016/j.mce.2017.09.009</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Nikolakis G., Kyrgidis A., Zouboulis C.C. Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data. Am J Clin Dermatol. 2019;20(4):503–13. https://dx.doi.org/10.1007/s40257-019-00442-w</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Yook H.J., Kim E., Kim Y.H., et al. A link between smoking behaviors and the risk of hidradenitis suppurativa in diabetic patients. PLoS One. 2025;20(6):e0325357. https://dx.doi.org/10.1371/journal.pone.0325357</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Ng-Wong Y.K., Alexander B., Bartl M., et al. Deeper Seated Than Skin Deep: Report of a Rare Case of Follicular Occlusion Tetrad and a Literature Review. Cureus. 2023;15(5):e39474. https://dx.doi.org/10.7759/cureus.39474</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Tricarico P.M., Boniotto M., Genovese G., et al. An Integrated Approach to Unravel Hidradenitis Suppurativa Etiopathogenesis. Front Immunol. 2019 Apr 25;10:892. https://dx.doi.org/10.3389/fimmu.2019.00892</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Liu T., Li S., Ying S., et al. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside. Front Immunol. 2020;11:594735. https://dx.doi.org/10.3389/fimmu.2020.594735</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Savage K.T., Flood K.S., Porter M.L., Kimball A.B. TNF-α inhibitors in the treatment of hidradenitis suppurativa. Ther Adv Chronic Dis. 2019;10:2040622319851640. https://dx.doi.org/10.1177/2040622319851640</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Ingram J.R. The epidemiology of hidradenitis suppurativa. Br J Dermatol. 2020;183(6):990–8. https://dx.doi.org/10.1111/bjd.19435</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Хайрутдинов В.Р., Бурова С.А., Олисова О.Ю. и др. Гнойный гидраденит: обзор международных клинических рекомендаций по диагностике и лечению заболевания. Вестник дерматологии и венерологии. 2024;100(3):7–16. [Khairutdinov V.R., Burova S.A., Olisova O.Yu., et al. Suppurative hidradenitis: a review of international clinical guidelines for the diagnosis and treatment of the disease. Bulletin of Dermatology and Venereology. 2024;100(3):7–16. (In Russ.)]. https://doi.org/10.25208/vdv16739</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Клинические рекомендации. Гидраденит гнойный. Год утверждения 2023. [Clinical guidelines. Suppurative hidradenitis. Year of approval 2023. (In Russ.)].</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Mahmood F., Hussain A., Akingboye A. Pilonidal sinus disease: Review of current practice and prospects for endoscopic treatment. Ann Med Surg (Lond). 2020;57:212–7. https://dx.doi.org/10.1016/j.amsu.2020.07.050</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Magalhães R.F., Rivitti-Machado M.C., Duarte G.V., et al. Consensus on the treatment of hidradenitis suppurativa - Brazilian Society of Dermatology. An Bras Dermatol. 2019;94(2 Suppl. 1):7–19. https://dx.doi.org/10.1590/abd1806-4841.20198607</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Alikhan A., Sayed C., Alavi A., et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. J Am Acad Dermatol. 2019;81(1):91–101. https://dx.doi.org/10.1016/j.jaad.2019.02.068</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Baran A., Kwiatkowska A., Potocki L. Antibiotics and Bacterial Resistance-A Short Story of an Endless Arms Race. Int J Mol Sci. 2023;24(6):5777. https://dx.doi.org/10.3390/ijms24065777</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Goldburg S.R., Strober B.E., Payette M.J. Hidradenitis suppurativa: Current and emerging treatments. J Am Acad Dermatol. 2020;82(5):1061–82. https://dx.doi.org/10.1016/j.jaad.2019.08.089</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Alshehri A.A., Althobaiti B.A., Khawagi W.Y., Murphy K.D. Awareness of isotretinoin use and safety in Saudi Arabia: A nationwide cross-sectional study. Saudi Pharm J. 2023;31(11):101796. https://dx.doi.org/10.1016/j.jsps.2023.101796</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Zouboulis C.C., Bechara F.G., Dickinson-Blok J.L., et al. Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization - systematic review and recommendations from the HS ALLIANCE working group. J Eur Acad Dermatol Venereol. 2019;33(1):19–31. https://dx.doi.org/10.1111/jdv.15233</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Lucky A.W., Koltun W., Thiboutot D., et al. A combined oral contraceptive containing 3-mg drospirenone/ 20-microg ethinyl estradiol in the treatment of acne vulgaris: a randomized, double-blind, placebo-controlled study evaluating lesion counts and participant self-assessment. Cutis. 2008;82(2):143–50.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Riis P.T., Ring H.C., Themstrup L., Jemec G.B. The Role of Androgens and Estrogens in Hidradenitis Suppurativa - A Systematic Review. Acta Dermatovenerol Croat. 2016;24(4):239–49.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Hambly R., Kearney N., Hughes R., et al. Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators. Int J Mol Sci. 2023;24(8):6969. https://dx.doi.org/10.3390/ijms24086969</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Petrasca A., Hambly R., Kearney N., et al. Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa, Br J Dermatol. 2023;189(6):730–40. https://doi.org/10.1093/bjd/ljad305</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Hendricks A.J., Hsiao J.L., Lowes M.A., Shi V.Y. A Comparison of International Management Guidelines for Hidradenitis Suppurativa. Dermatology. 2021;237(1):81–96. https://dx.doi.org/10.1159/000503605</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Alikhan A., Sayed C., Alavi A., et al. North American clinical management guidelines for hidradenitis suppurativa: a publication from the United States and Canadian hidradenitis suppurativa foundations: Part I: diagnosis, evaluation, and the use of complementary and procedural management. J Am Acad Dermatol. 2019;81(1):76–90. https://dx.doi.org/10.1016/j.jaad.2019.02.067</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Chawla S., Toale C., Мorris М., et al. Surgical management of hidradenitis suppurativa: a narrative review. J Clin Aesthet Dermatol. 2022;15(1):35–41.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Yeroushalmi S., Ildardashty A., Elhage K.G., et al. Hidradenitis suppurativa and sleep: a systematic review. Arch Dermatol Res. 2023;315(5):1409–15. https://dx.doi.org/10.1007/s00403-022-02460-x</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Di Guida A., Forgione P., Fornaro L., et al. Step by step surgery for hidradenitis suppurativa. Dermatol Ther. 2022;35(12):e15938. https://dx.doi.org/10.1111/dth.15938</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Guermazi D., Shah A., Yumeen S., Saliba E. The use of biologics and JAK inhibitors in the management of moderate to severe Hidradenitis Suppurativa treatment: a scoping review. Arch Dermatol Res. 2024;316(6):259. https://dx.doi.org/10.1007/s00403-024-03121-x</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Zouboulis C.C., Okun M.M., Prens E.P., et al. Long-term adalimumab efficacy in patients with moderate-to-severe hidradenitis suppurativa/acne inversa: 3-year results of a phase 3 open-label extension study. J Am Acad Dermatol. 2019;80(1):60–9.e2. https://dx.doi.org/10.1016/j.jaad.2018.05.040</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Zouboulis C.C., Bechara F.G., Dickinson-Blok J.L., et al. Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization - systematic review and recommendations from the HS ALLIANCE working group. J Eur Acad Dermatol Venereol. 2019;33(1):19–31. https://dx.doi.org/10.1111/jdv.15233</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Schettini N., Marzola E., Pacetti L., et al. Case of Dissecting Cellulitis of the Scalp, Hidradenitis Suppurativa, and Conglobate Acne Successfully Treated with Secukinumab. Skin Appendage Disord. 2024;10(3):232–5. https://dx.doi.org/10.1159/000537914</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Snyder C.L., Gibson R.S., Porter M.L., Kimball A.B. Secukinumab in the treatment of hidradenitis suppurativa. Immunotherapy. 2023;15(17):1449–57. https://dx.doi.org/10.2217/imt-2023-0103</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>Stergianou D., Kanni T., Damoulari C., et al. arellos-Bourboulis E.J. An evaluation of secukinumab for the treatment of moderate-to-severe hidradenitis suppurativa. Expert Opin Biol Ther. 2024;24(4):225–32. https://dx.doi.org/10.1080/14712598.2024.2343112</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Lipa K., Zajac N., Witkowski G., et al. Hidradenitis suppurativa – biologic therapy and other available treatment options. Postepy Dermatol Alergol. 2023;40(4):518–28. https://dx.doi.org/10.5114/ada.2021.112075</mixed-citation></ref><ref id="B49"><label>49.</label><mixed-citation>Hendricks A.J., Hsiao J.L., Lowes M.A., Shi V.Y. A Comparison of International Management Guidelines for Hidradenitis Suppurativa. Dermatology. 2021;237(1):81–96. https://dx.doi.org/10.1159/000503605</mixed-citation></ref><ref id="B50"><label>50.</label><mixed-citation>Hurley H.J. Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: Surgical approach. In: Dermatologic Surgery: Principles and Practice, Roenigk R.K., Roenigk H.H. (Eds), Marcel Dekker. 1989. 729 p.</mixed-citation></ref><ref id="B51"><label>51.</label><mixed-citation>Prens L.M., Rondags A., Volkering R.J., et al. The refined Hurley classification: the inter-rater and intrarater reliability and face validity. Br J Dermatol. 2019;181(6):1335–7. https://dx.doi.org/10.1111/bjd.18235</mixed-citation></ref></ref-list></back></article>
