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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">691260</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2025.5.56-59</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical experience</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинический опыт</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Physiotherapeutic approach in the treatment of rosacea. Modern approaches to the treatment of rosacea through the prism of pathogenesis</article-title><trans-title-group xml:lang="ru"><trans-title>Физиотерапевтический подход в лечении розацеа. Современные подходы терапии розацеа через призму патогенеза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4426-1934</contrib-id><contrib-id contrib-id-type="spin">7131-3022</contrib-id><name-alternatives><name xml:lang="en"><surname>Khanalieva</surname><given-names>Isita A.</given-names></name><name xml:lang="ru"><surname>Ханалиева</surname><given-names>Исита Адылмажитовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dermatologist, Cosmetologist, Plastic Surgeon, Ultrasound Doctor; assistant of the Department of Skin and Venereal Diseases</p></bio><bio xml:lang="ru"><p>врач-дерматолог, косметолог, пластический хирург, врач УЗД; ассистент кафедры кожных и венерических болезней</p></bio><email>doctor.khanalieva@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5885-4872</contrib-id><name-alternatives><name xml:lang="en"><surname>Svechnikova</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Свечникова</surname><given-names>Елена Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor of the Department of Skin and Venereal Diseases; Head of the Department of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>д.м.н., профессор кафедры кожных и венерических болезней; зав. отделением дерматовенерологии и косметологии</p></bio><email>doctor.khanalieva@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3087-5038</contrib-id><name-alternatives><name xml:lang="en"><surname>Gladko</surname><given-names>Viktor V.</given-names></name><name xml:lang="ru"><surname>Гладько</surname><given-names>Виктор Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of the Department of Skin and Venereal Diseases with a Course in Cosmetology, Medical Institute of Continuous Education</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой кожных и венерических болезней с курсом косметологии МИНО</p></bio><email>dr.gladko@mgupp.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Izmaylova</surname><given-names>Irina V.</given-names></name><name xml:lang="ru"><surname>Измайлова</surname><given-names>Ирина Валентиновна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor at the Department of Skin and Venereal Diseases with a Course in Cosmetology</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры кожных и венерических болезней с курсом косметологии МИНО</p></bio><email>izmajjlovaiv@mgupp.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Biotechnological University</institution></aff><aff><institution xml:lang="ru">Российский биотехнологический университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Polyclinic № 1 of the Administrative Directorate of the President of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Поликлиника № 1 Управления делами Президента РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-09-24" publication-format="electronic"><day>24</day><month>09</month><year>2025</year></pub-date><volume>32</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>56</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2025-09-23"><day>23</day><month>09</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-09-23"><day>23</day><month>09</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ООО «Бионика Медиа»</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/691260">https://journals.eco-vector.com/2073-4034/article/view/691260</self-uri><abstract xml:lang="en"><p>Rosacea is a chronic dermatological disorder characterized by recurrent inflammatory episodes and vascular alterations. One of the promising therapeutic approaches for this condition is light-based therapy, particularly the use of intense pulsed light (IPL) technology. This method has demonstrated significant efficacy in reducing the severity of vascular and inflammatory manifestations, while maintaining a favorable safety profile. Despite the well-established clinical effectiveness of IPL therapy in managing rosacea, optimization of treatment parameters remains an ongoing challenge. This article presents current evidence on the efficacy of IPL therapy for rosacea treatment, explores the pathogenesis and key procedural parameters of this method, and shares our experience with advanced technological solutions in this field.</p></abstract><trans-abstract xml:lang="ru"><p>Розацеа представляет собой хроническое дерматологическое заболевание, характеризующееся рецидивирующими воспалительными реакциями и сосудистыми изменениями. Одним из перспективных направлений в лечении данного заболевания является световая терапия, в частности использование технологии IPL (интенсивного импульсного света). Данная методика демонстрирует высокие результаты в снижении выраженности сосудистых и воспалительных проявлений, а также характеризуется высоким профилем безопасности. Несмотря на доказанную клиническую эффективность применения IPL-терапии в лечении розацеа, вопросы оптимизации параметров процедуры по-прежнему остаются актуальными. В настоящей статье представлены современные данные об эффективности применении IPL-терапии для лечения розацеа, патогенез и основные параметры данной методики, а также представлен наш опыт использования передовых технологических решений в данной области.</p></trans-abstract><kwd-group xml:lang="en"><kwd>rosacea</kwd><kwd>IPL- therapy</kwd><kwd>light-based therapy</kwd><kwd>efficacy</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>розацеа</kwd><kwd>IPL-терапия</kwd><kwd>световая терапия</kwd><kwd>эффективность</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Geng R.S.Q., Bourkas A.N., Mufti A., Sibbald R.G. Rosacea: pathogenesis and therapeutic correlates. J Cutan Med Surg. 2024;28(2):178–189. https://dx.doi.org/10.1177/12034754241229365</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hofmann M.A., Lehmann P. Physical modalities for the treatment of rosacea. J Dtsch Dermatol Ges. 2016;14 Suppl 6:38–43. https://dx.doi.org/10.1111/ddg.13144</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Babilas P., Schreml S., Szeimies R.M., Landthaler M. Intense pulsed light (IPL): a review. Lasers Surg Med. 2010;42(2):93–104. https://dx.doi.org/10.1002/lsm.20877</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Martignago C.C.S., Bonifacio M., Ascimann L.T., et al. Efficacy and safety of intense pulsed light in rosacea: a systematic review. Indian J Dermatol Venereol Leprol. 2024;90:599–605. https://dx.doi.org/10.25259/IJDVL_1029_2022</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Liu J., Liu J., Ren Y., Li B., Lu S. Comparative efficacy of intense pulsed light for different erythema associated with rosacea. J Cosmet Laser Ther. 2014;16:324–327. https://dx.doi.org/10.3109/14764172.2014.957218</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Luo Y., Luan X.L., Zhang J.H., et al. Improved telangiectasia and reduced recurrence rate of rosacea after treatment with 540 nm-wavelength intense pulsed light: a prospective randomized controlled trial with a 2-year follow-up. Exp Ther Med. 2020;19:3543–3550. https://dx.doi.org/10.3892/etm.2020.8617</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Dinsdale G., Murray A., Moore T., et al. A comparison of intense pulsed light and laser treatment of telangiectases in patients with systemic sclerosis: a within-subject randomized trial. Rheumatol (Oxford). 2014;53:1422–1430. https://dx.doi.org/10.1093/rheumatology/keu006</mixed-citation></ref></ref-list></back></article>
