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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">717311</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2026.4.172-178</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Obstetrics/gynecology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Акушерство/гинекология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Sphincter-levatorplasty as a method for correcting anal incontinence in women. Review</article-title><trans-title-group xml:lang="ru"><trans-title>Сфинктеролеваторопластика как метод коррекции анальной инконтиненции у женщин. Обзор</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3899-8382</contrib-id><name-alternatives><name xml:lang="en"><surname>Glukhov</surname><given-names>Evgeny Y.</given-names></name><name xml:lang="ru"><surname>Глухов</surname><given-names>Евгений Юрьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Chief Physician, Professor, Department of Obstetrics and Gynecology with a Course in Medical Genetics</p></bio><bio xml:lang="ru"><p>д.м.н., главный врач, профессор кафедры акушерства и гинекологии с курсом медицинской генетики</p></bio><email>9222241411@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-9542-5184</contrib-id><name-alternatives><name xml:lang="en"><surname>Khizadze</surname><given-names>Artem G.</given-names></name><name xml:lang="ru"><surname>Хизадзе</surname><given-names>Артем Георгиевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Obstetrician-Gynecologist</p></bio><bio xml:lang="ru"><p>врач акушер-гинеколог</p></bio><email>khizadze.artem@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-6360-9044</contrib-id><name-alternatives><name xml:lang="en"><surname>Kurkova</surname><given-names>Tatyana F.</given-names></name><name xml:lang="ru"><surname>Куркова</surname><given-names>Татьяна Фикретовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Obstetrician-gynecologist, Ultrasound Diagnostics Specialist</p></bio><bio xml:lang="ru"><p>врач акушер-гинеколог, врач ультразвуковой диагностики</p></bio><email>kurkovagyn@ya.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-1656-5411</contrib-id><name-alternatives><name xml:lang="en"><surname>Glukhova</surname><given-names>Victoria E.</given-names></name><name xml:lang="ru"><surname>Глухова</surname><given-names>Виктория Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Head of the Ultrasound Diagnostics Department</p></bio><bio xml:lang="ru"><p>зав. отделением ультразвуковой диагностики</p></bio><email>gluhovav17@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Ural State Medical University, Institute of Pediatrics and Reproductive Medicine</institution></aff><aff><institution xml:lang="ru">Уральский государственный медицинский университет, Институт педиатрии и репродуктивной медицины</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Center for Reconstructive Gynecology «Women’s Clinic»</institution></aff><aff><institution xml:lang="ru">Центр восстановительной гинекологии «Женская клиника»</institution></aff></aff-alternatives><content-language>ru</content-language><pub-date date-type="pub" publication-format="electronic" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></pub-date><pub-date date-type="collection"><year>2026</year></pub-date><volume>33</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>172</fpage><lpage>178</lpage><history><date date-type="received" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></date><date date-type="accepted" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></date></history><pub-history><event event-type="received"><event-desc>Received:<date date-type="received" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></date></event-desc></event><event event-type="accepted"><event-desc>Accepted:<date date-type="accepted" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></date></event-desc></event><event event-type="pub"><event-desc>Published:<pub-date date-type="pub" publication-format="electronic" iso-8601-date="2026-08-17"><day>17</day><month>08</month><year>2026</year></pub-date></event-desc></event></pub-history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, ООО «Бионика Медиа»</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://journals.eco-vector.com/2073-4034/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/717311">https://journals.eco-vector.com/2073-4034/article/view/717311</self-uri><abstract xml:lang="en"><p><bold>Background: </bold>Anal incontinence is a common problem in women who have suffered perineal trauma during childbirth. Symptoms of anal incontinence are socially disabling and significantly reduce quality of life.</p> <p><bold>Key findings: </bold>Current understanding of anal incontinence necessitates in-depth knowledge of the functioning of the rectal sphincter apparatus and diagnostic and therapeutic approaches to this problem. Surgical treatment of anal sphincter insufficiency includes various sphincteroplasty options, including restoration of the levator ani muscle. The long-term effectiveness of surgical correction of sphincter insufficiency varies; early and detailed diagnosis of muscle defects and functional impairments improves treatment outcomes, allowing for the development of an individualized, multimodal treatment approach. Alternative techniques (sacral neuromodulation, artificial sphincter implantation, and graciloplasty) are used in cases with severe damage, anal sphincter denervation, and in cases where other techniques have proven ineffective.</p> <p><bold>Conclusion:</bold> Modern approaches to sphincteroplasty focus on restoring anatomy and function, taking into account individual characteristics, with the choice of technique based on a balance between its benefits and potential risks.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование: </bold>Анальная инконтиненция является распространенной проблемой у женщин, перенесших травму промежности в родах. Симптомы недержания кишечного содержимого являются социально дезадаптирующими и значимо снижают качество жизни.</p> <p><bold>Основные результаты: </bold>Современное понимание проблемы анальной инконтиненции диктует врачам необходимость глубоких знаний в функционировании запирательного аппарата прямой кишки, диагностических и лечебных подходах к данной проблеме.</p> <p>Хирургическое лечение недостаточности анального сфинктера включает различные варианты сфинктеропластики, в т.ч. с восстановлением мышцы, поднимающей задний проход. Отдаленная эффективность оперативной коррекции сфинктерной недостаточности варьирует, улучшить результаты лечения позволяет ранняя и детальная диагностика мышечных дефектов и функциональных нарушений с целью выработки индивидуализированного мультимодального подхода к лечению. Альтернативные методики (сакральная нейромодуляция, имплантация искусственного сфинктера, грацилопластика) имеют место в кейсах с тяжелым повреждением, денервацией анального сфинктера, а также в случаях, где другие технологии оказались неэффективны.</p> <p><bold>Заключение: </bold>Современные подходы к сфинктеропластике ориентированы на восстановление анатомии и функции с учетом индивидуальных особенностей, при этом выбор методики основывается на балансе между ее преимуществами и возможными рисками.</p></trans-abstract><kwd-group xml:lang="en"><kwd>anal incontinence</kwd><kwd>fecal incontinence</kwd><kwd>patient-centered treatment</kwd><kwd>sphincteroplasty</kwd><kwd>levatoroplasty</kwd><kwd>sphincter-levatoroplasty</kwd><kwd>quality of life</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>анальная инконтиненция</kwd><kwd>анальное недержание</kwd><kwd>пациентоориентированное лечение</kwd><kwd>сфинктеропластика</kwd><kwd>леваторопластика</kwd><kwd>сфинктеролеваторопластика</kwd><kwd>качество жизни</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Маркарян Д.Р., Лукьянов А.М., Гарманова Т.Н. и др. Послеродовое анальное недержание. Состояние проблемы. Хирургия. Журнал им. Н.И. Пирогова. 2022;(6):127-132. [Markaryan D.R., Lukyanov A.M., Garmanova T.N., et al. Postpartum anal incontinence. State of the problem. Surgery. Zhurnal im. N.I. Pirogov. 2022;(6):127-132. (In Russ.)]. https://dx.doi.org/10.17116/hirurgia2022061127</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Blackett J.W., Bharucha A.E. Fecal Incontinence in Adults: New Therapies. Am J Gastroenterol. 2025;120:2027-2041. https://dx.doi.org/10.14309/ajg.0000000000003413</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Whitehead W.E., Palsson O.S., Simren M. Treating Fecal Incontinence: An Unmet Need in Primary Care Medicine. N C Med J. 2016;77(3):211-215. https://dx.doi.org/10.18043/ncm.77.3.211</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Halani P.K., Wilson L., Cadish L.A., et al Impact of social determinants of health on fecal incontinence treatment in older women. Am J Obstet Gynecol. 2025;233(6):645.e1-645.e13. https://dx.doi.org/10.1016/j.ajog.2025.07.006.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Li H.L., Zhang H.R., Wu Y., et al. Anal sphincter reconstruction for fecal incontinence: Techniques, outcomes, and future directions. World J Gastrointest Surg. 2025;17(11):112868. https://dx.doi.org/10.4240/wjgs.v17.i11.112868</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Parks A.G. Anorectal incontinence. Proc R Soc Med. 1975;68(11):681-690. https://dx.doi.org/10.1177/003591577506801105</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Snooks S..J., Setchell M., Swash M., Henry M.M. Injury to innervation of pelvic floor sphincter musculature in childbirth. Lancet. 1984;2(8402):546-550. https://dx.doi.org/10.1016/S0140-6736(84)90766-9</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Allen R.E., Hosker G.L., Smith A.R.B., Warrell D.W. Pelvic floor damage and childbirth: a neurophysiological study. Br J Obstet Gynaecol. 1990;97:770-779. https://dx.doi.org/10.1111/j.1471-0528.1990.tb02570.x</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Dudding T.C., Vaizey C.J., Kamm M.A. Obstetric anal sphincter injury: incidence, risk factors, and management. Ann Surg. 2008;247(2):224-237. https://dx.doi.org/10.1097/SLA.0b013e318142cdf4</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Spinelli A., Laurenti V., Carrano F.M., et al. Diagnosis and Treatment of Obstetric Anal Sphincter Injuries: New Evidence and Perspectives. J Clin Med. 2021;10(15):3261. https://dx.doi.org/10.3390/jcm10153261</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Cattani L., Neefs L., Verbakel J.Y., et al. Obstetric risk factors for anorectal dysfunction after delivery: a systematic review and meta-analysis. Int Urogynecol J. 2021;32(9):2325-2336. https://dx.doi.org/10.1007/s00192-021-04723-z</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Sultan A.H., Kamm M.A., Hudson C.N., Bartram C.I. Third degree obstetric anal sphincter tears: risk factors and outcome of primary repair. BMJ. 1994;308:887-891. https://dx.doi.org/10.1136/bmj.308.6933.887</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Gurol-Urganci I., Cromwell D.A., Edozien L.C., et al. Third- and fourth-degree perineal tears among primiparous women in England between 2000 and 2012: time trends and risk factors. BJOG. 2013;120:1516-1525. https://dx.doi.org/10.1111/1471-0528.12363</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Bordeianou L.G., Thorsen A.J., Keller D.S., et al. Clinical practice guidelines for the management of fecal incontinence. Dis Colon Rectum. 2023;66(5):647-661. https://dx.doi.org/10.1097/DCR.0000000000002776</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Taithongchai A., van Gruting I.M.A., Volløyhaug I., et al. Comparing the diagnostic accuracy of 3 ultrasound modalities for diagnosing obstetric anal sphincter injuries. Am J Obstet Gynecol. 2019;221(2):134.e1-134.e9. https://dx.doi.org/10.1016/j.ajog.2019.04.009</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Carrington E.V., Heinrich H., Knowles C.H., et al. The international anorectal physiology working group (IAPWG) recommendations: standardized testing protocol and the London classification for disorders of anorectal function. Neurogastroenterol Motil. 2020;32(1):e13679. https://dx.doi.org/10.1111/nmo.13679</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Schwandner T., Hemmelmann C., Heimerl T., et al. Triple-target treatment versus low-frequency electrostimulation for anal incontinence: a randomized, controlled trial. Dtsch Arztebl Int. 2011;108(39):653-660. https://dx.doi.org/10.3238/arztebl.2011.0653</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Simillis C., Lal N., Pellino G., Baird D., et al. A systematic review and network meta-analysis comparing treatments for faecal incontinence. Int J Surg. 2019;66:37-47. https://dx.doi.org/10.1016/j.ijsu.2019.04.007</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Parks A.G., McPartlin J.F. Late repair of injuries of the anal sphincter. Proc R Soc Med. 1971;64(12):1187-1189. https://dx.doi.org/10.1177/003591577106401205</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Fang D.T., Nivatvongs S., Vermeulen F.D., et al. Overlapping sphincteroplasty for acquired anal incontinence. Dis Colon Rectum. 1984;27(11):720-722. https://dx.doi.org/10.1007/BF02554596</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Pescatori L.C., Pescatori M. Sphincteroplasty for anal incontinence. Gastroenterol Rep (Oxf). 2014;2(2):92-97. https://dx.doi.org/10.1093/gastro/gou003</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Miller R., Orrom W.J., Cornes H., et al. Anterior sphincter plication and levatorplasty in the treatment of faecal incontinence. Br J Surg. 1989;76(10):1058-1060. https://dx.doi.org/10.1002/bjs.1800761024</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Osterberg A., Graf W., Holmberg A., et al. Long-term results of anterior levatorplasty for fecal incontinence. A retrospective study. Dis Colon Rectum. 1996;39(6):671-674. https://dx.doi.org/10.1007/BF02056948</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Evans C., Davis K., Kumar D. Overlapping anal sphincter repair and anterior levatorplasty: effect of patient’s age and duration of follow-up. Int J Colorectal Dis. 2006;21(8):795-801. https://dx.doi.org/10.1007/s00384-006-0101-1</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Santacruz C.C., Cerdan Santacruz D.M., Milla Collado L., et al. Multimodal Management of Fecal Incontinence Focused on Sphincteroplasty: Long-Term Outcomes from a Single Center Case Series. J Clin Med. 2022;11(13):3755. https://dx.doi.org/10.3390/jcm11133755</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Berkesoglu M., Colak T., Turkmenoglu M.O., et al. Long-term results from modified sphincteroplasty in patients with traumatic sphincter injury: a retrospective study. Sao Paulo Med J. 2021;139(1):58-64. https://dx.doi.org/10.1590/1516-3180.2020.0467.02112020</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Alketbi M.S.G.h., Meyer J., Robert-Yap J., et al. Levator ani and puborectalis muscle rupture: diagnosis and repair for perineal instability. Tech Coloproctol. 2021;25(8):923-933. https://dx.doi.org/10.1007/s10151-020-02392-6</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Berg M.R., Gregussen H., Sahlin Y. Long-term outcome of sphincteroplasty with separate suturing of the internal and the external anal sphincter. Tech Coloproctol. 2019;23(12):1163-1172. https://dx.doi.org/10.1007/s10151-019-02122-7</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Fernando R.J., Sultan A.H., Kettle C., et al. Methods of repair for obstetric anal sphincter injury. Cochrane Database Syst Rev. 2006;(3):CD002866. https://dx.doi.org/10.1002/14651858.CD002866.pub2</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Farrell S.A., Flowerdew G., Gilmour D., et al. Overlapping compared with end-to-end repair of complete third-degree or fourth-degree obstetric tears: three-year follow-up of a randomized controlled trial. Obstet Gynecol. 2012;120(4):803-808. https://dx.doi.org/10.1097/AOG.0b013e31826ac4bb</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Haug H.M., Carlsen E., Johannessen H.O., Johnson E. Short-, long-, and very long-term results of secondary anterior sphincteroplasty in 20 patients with obstetric injury. Int J Colorectal Dis. 2021;36(12):2775-2778. https://dx.doi.org/10.1007/s00384-021-04026-1</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Bergna A., Rusconi A., Megevand J., et al. Comparative outcomes of sphincteroplasty and sacral neuromodulation in postmenopausal women with late-onset fecal incontinence following obstetric trauma: a retrospective study. Updates Surg. 2025 Jul 5. https://dx.doi.org/10.1007/s13304-025-02317-8</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Emile S.H., Wignakumar A., Horesh N., et al. Efficacy of Sacral Neuromodulation in Treatment of Fecal Incontinence Associated With Anal Sphincter Defects: A Systematic Review and Meta-Analysis. World J Surg. 2026;50(1):48-57. https://dx.doi.org/10.1002/wjs.70152</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Meyer I., Richter H.E. Impact of fecal incontinence and its treatment on quality of life in women. Womens Health (Lond). 2015;11(2):225-238. https://dx.doi.org/10.2217/whe.14.66</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Chapman A.E., Geerdes B., Hewett P., et al. Systematic review of dynamic graciloplasty in the treatment of faecal incontinence. Br J Surg. 2002;89(2):138-153.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Fattorini E., Brusa T., Gingert C., et al. Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment. Ann Biomed Eng. 2016;44(5):1355-1369. https://dx.doi.org/10.1007/s10439-016-1572-z</mixed-citation></ref></ref-list></back></article>
