Ingibitory SGLT-2: farmakologicheskaya glyukozuriya kak novyy podkhod v upravlenii SD 2 tipa
- Authors: Demidova T.Y.1
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Affiliations:
- Issue: No 5 (2015)
- Pages: 12-19
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/287805
- ID: 287805
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Abstract
Progressive course of type 2 diabetes mellitus, the lack of an «ideal» drug for the treatment of this disease are a key factors for the searching of new opportunities for effective management of blood glucose. The emergence of a new class of oral antidiabetic drugs is always an outstanding event in the modern diabetology The appearance of sodium-glucose co-transporter type 2 inhibitors and their introduction into clinical practice open a new era in the treatment of diabetes. Dapagliflozin is the first representative of this class, registered in Russia. With the best risk/benefit ratio and unique insulin-independent mechanism of action, dapagliflozin provides new opportunities to control not only the level of glycemia, but body weight without increasing the risk of hypoglycemia both foe physicians and patients.
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