Possibilities and features of injection therapy of knee osteoarthritis


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Abstract

The article discusses the problem of osteoarthritis (OA), one of the most common chronic non-infectious diseases of joints among the older population. Data on epidemiology, classification, pathogenesis, and treatment of OA are presented. In case of progressive course of knee OA, when conservative treatment methods fail to achieve the desired result, it is reasonable to perform invasive intraarticular injections of active drugs such as glucocorticosteroids, hyaluronic acid, chondroitin sulfate, and platelet-rich plasma.

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About the authors

E. G Zotkin

V.A. Nasonova Research Institute of Rheumatology; North-Western State Medical University n.a. I.I. Mechnikov

Email: ezotkin@mail.ru
MD

References

  1. Felson D.T. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin. Arthritis Rheum. 1990;20(3 Suppl. 1):42-50.
  2. van Saase J.L., van Romunde L.K., Cats A., et al. Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations. Ann. Rheum. Dis. 1989;48(4):271-80.
  3. Felson D.T. Epidemiology of hip and knee osteoarthritis. Epidemiol. Rev.1988;10:1-28.
  4. Goldring M.B., Goldring S.R. Osteoarthritis. J. Cell. Physiol. 2007;213;626-34.
  5. Archer C.W, Francis-West P. The chondrocyte. Int. J. Biochem. Cell Biol. 2003;35:401-4.
  6. Speziali A., Delcogliano M., Tei М., et al. Chondropenia: Current concept review. Musculoskelet. Surg. 2015;99:189-200.
  7. Goldring M.B., Otero M., Plumb D.A., et al. Roles of inflammatory and anabolic cytokines in cartilage metabolism: Signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. Eur. Cells Mater. 2011; 21:202-20.
  8. Bruyere O., Cooper C.C., Pelletier J.-P., et.al. An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Sem. Arthr. Rheum. 2014; 44:252-63.
  9. Jüni P., Hari R., Rutjes A.W.S., et al. Intra-articular corticosteroid for knee osteoarthritis. Cochrane Database of Systematic Reviews. 2015;lssue 10:CD005328.
  10. Goldenberg V.M., Bucwalter J.A. Hyaluronans in the treatment of osteoarthritis of the knee: evidence for disease-modifying activity. Osteoarthritis and Cartilage. 2005;13:216-24.
  11. Bellamy N., Campbell J., Robinson V., et al. lntraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst. Rev. 2006.
  12. Navarro-Sarabia F., Coronel P., Collantes E., et al. A 40-month multicentre, randomized placebo-controlled study to assess the efficacy and carry-over effect of repeated intra-articular injections of hyaluronic acid in knee osteoarthritis: the AMELIA project. Ann. Rheum. Dis. 2011;70:1957-62.
  13. Rivera F., Bertignone L., Grandi G., et al. Effectiveness of intra-articular injections of sodium hyaluronate chondroitin sulfate in knee osteoarthritis: a multicenter prospective study. J. Orthopaed. Traumatol. 2016;17:27-33.
  14. Maheu E., Rannou F., Reginster J.Y. Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin. Arthritis Rheum. 2016;45:28-33.
  15. Bali J.P., Cousse H., Neuzil E. Biochemical basis of the pharmacologic action of chondroitin sulfates on the osteoarticular system. Semin. Arthritis Rheum. 2001;31(1):58-68.
  16. Волошин В.П., Еремин А.В., Санкаранараянан С.А., Тукаев М.Ю., Садовый И.В., Бардюгов П.С., Темесов С.А. Исследование эффективности препарата хондроитина сульфат у пациентов с остеоартрозом. РМЖ. 2015;10:575.
  17. Shang Q., Yin Y., Zhu L., et al. Degradation of chondroitin sulfate by the gut microbiota of Chinese individuals. Int. J. Biol. Macromol. 2016;86:112-18. doi: 10.1016/j.ijbiomac.2016.01.055. Epub 2016Jan 19.
  18. Ronca F., Palmieri L., Panicucci P. Ronca G. Antiinflammatory activity of chondroitin sulfate. Osteoarthritis Cartilage. 1998;6:14-21.
  19. Dieppe P., Goldingay S., Greville-Harris M. The power and value of placebo and nocebo in painful osteoarthritis. Osteoarthritis Cartilage. 2016;24(11): 1850-57.
  20. Shen L., Yuan T., Chen S., et al. The temporal effect of platelet-rich plasma on pain and physical function in the treatment of knee osteoarthritis: systematic review and meta-analysis of randomized controlled trials. J. Orthopaed. Surg. Res. 2017;12(16):1-12.

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