Malignant melanoma detected during follow-up: literature review and cases report
- Authors: Sergeev Y.Y.1,2, Beinusov D.S1, Mordovtseva V.V1,3, Sergeev V.Y.1,2
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Affiliations:
- Society of Dermatoscopy and Optical Diagnostics of the Skin
- Central State Medical Academy of Department of Presidential Affairs
- Moscow State University of Food Production
- Issue: Vol 28, No 14 (2021)
- Pages: 34-41
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/313334
- DOI: https://doi.org/10.18565/pharmateca.2021.14.34-41
- ID: 313334
Cite item
Abstract
The article discusses the possibility of timely diagnosis of malignant melanoma by assessing changes in the dermatoscopic picture of formations during follow-up. An analysis of 23 cases from authors’ own practice, identified mainly in patients at risk, is given. The age of the patients varied from 28 to 70 years, mean age 36.7±10.5 years. Follow-up of pigmented lesions before making a decision on excision was performed out for 3-24 months, on average - 10.5±5.4 months. Changes in the dermatoscopic picture were manifested by an asymmetric increase of the lesion and/or a change of its shape (43.5%), the appearance of a new color (69.6%), the formation of an atypical dermatoscopic structure (65.2%), a change in the pattern of the pigment network (56.5 %), modification of the dermatoscopic model of the structure (21.7%), partial regression of formation (4.3%). The mean diameter of the lesions during the follow-up period increased from 4.2±2.2 to 5.4±2.3 mm, the lesion value of the total dermoscopic score of the ABCD rule increased from 3.4±0.9 to 4.6±1.2 points (P<0.05). Histological examination diagnosed melanoma in situ in 52.2% of cases, in the rest - microinvasive melanoma (Clark level II) with Breslow thickness range from 0.2 to 0.5 mm.
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About the authors
Yuri Yu. Sergeev
Society of Dermatoscopy and Optical Diagnostics of the Skin; Central State Medical Academy of Department of Presidential Affairs
Email: tosergeev@gmail.com
D. S Beinusov
Society of Dermatoscopy and Optical Diagnostics of the Skin
V. V Mordovtseva
Society of Dermatoscopy and Optical Diagnostics of the Skin; Moscow State University of Food Production
V. Yu Sergeev
Society of Dermatoscopy and Optical Diagnostics of the Skin; Central State Medical Academy of Department of Presidential Affairs
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