The potential of SPECT/CT examination in detecting benign bone changes using clinical cases as an example

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Abstract

Bone scintigraphy is a highly sensitive but low-specific diagnostic method. It is noted that single-photon emission computed tomography combined with computed tomography (SPECT/CT) has greater sensitivity and accuracy compared to planar scintigraphy. The article presents differential diagnostics of focal bone changes detected by planar bone scintigraphy using clinical cases, carried out using the hybrid diagnostic method SPECT/CT, due to which benign changes in the skeletal system were detected. Thus, SPECT/CT examination allows to detect not only foci of malignant neoplasms, but also changes of benign nature, which is especially important in differential diagnostics of malignant and benign neoplasms.

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About the authors

Anastasia Yu. Litvinenko

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Author for correspondence.
Email: mau8aaa@mail.ru
ORCID iD: 0009-0004-7285-6040
Russian Federation, Chelyabinsk

N. G. Afanasyeva

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Email: mau8aaa@mail.ru
ORCID iD: 0000-0002-9432-5396
Russian Federation, Chelyabinsk

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Supplementary files

Supplementary Files
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2. Fig. 1. Osteoscintigraphy in the projection of the pubic bones of a 72-year-old patient

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3. Fig. 2. Osteoscintigraphy in the projection of the pubic bones of a 72-year-old patient (repeat examination after 3 months)

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4. Fig. 3. SPECT/CT examination of a patient, 72 years old

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5. Fig. 4. CT scan of a 72-year-old patient

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6. Fig. 5. SPECT/CT examination of a patient, 72 years old

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7. Fig. 6. CT scan of a 72-year-old patient

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8. Fig. 7. Bone scintigraphy of a 65-year-old female patient

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9. Fig. 8. SPECT/CT examination of a 65-year-old patient

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10. Fig. 9. CT scan of a 65-year-old female patient

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11. Fig. 10. SPECT/CT examination of a 65-year-old female patient

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12. Fig. 11. CT scan of a 65-year-old female patient

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13. Fig. 12. Bone scintigraphy of a patient with kidney cancer

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14. Fig. 13. SPECT/CT examination of a patient with kidney cancer

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15. Fig. 14. CT scan of a patient with kidney cancer

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