MODERN APPROACHES TO THE PREVENTION OF COPD EXACERBATION

The article describes the tactics of management of patients with chronic obstructive pulmonary disease (COPD). The data for the etiology, pathogenesis, and principles of diagnosis, treatment and prevention of this disease are presented. Supportive treatment of COPD involves the use of bronchodilators (sympathomimetics, cholinolytics, theophyllines), which should be preferably administered by inhalation. Patients with proven clinical or spirometric response to steroids should receive inhalation glucocorticoids. For prevention of COPD exacerbation, use of freeze-dried lysates of most common causative agents of respiratory tract infections, as well as N-acetylcysteine, is most effective. Targeted and systematic therapy provides a reduction in the risk of exacerbation and progression of COPD, relief of symptoms, increase in exercise tolerance, which generally lead to improvement of quality of life of patients.

chronic obstructive pulmonary disease, bronchodilators, glucocorticosteroids