INTEGRATED ASSESSMENT OF SAFETY OF TWO MODES OF ERADICATION THERAPY OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH CHRONIC HEPATITIS C
- Авторлар: Andreev D.N1, Maev I.V1, Dicheva D.T1, Kucheryavy Y.A1
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Мекемелер:
- SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPH
- Шығарылым: № 2 (2016)
- Беттер: 19-22
- Бөлім: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/288600
- ID: 288600
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
The article presents the results of a prospective randomized clinical study in parallel groups in which evaluated the safety of two modes of eradication therapy (ET) of Helicobacter pylori infection in patients with chronic hepatitis C (CHC) [OR - 1.40, 95% CI - 0,56-3,44]. The incidence of adverse events during the ET was higher in patients with concomitant HCV. In this group, patients had more frequent cumulative incidence of adverse events (n=28 vs n=18), regardless of the ET scheme appointed. ET have significant negative impact on the dynamics of biochemical markers of cytolytic and cholestatic syndromes, mostly in patients with concomitant HCV. Presence of hepatotoxic effect of drugs used for ET in some patients had no effect on the duration of treatment, but in order to avoid a significant drug-induced liver damage it is recommended to monitor the biochemical parameters during ET.
Негізгі сөздер
Толық мәтін
Авторлар туралы
D. Andreev
SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPH
Email: dna-mit8@mail.ru
Teaching Assistant of the Department of Propedeutics of Internal Diseases and Gastroenterology Moscow
I. Maev
SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPHMoscow
D. Dicheva
SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPHMoscow
Y. Kucheryavy
SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPHMoscow
Әдебиет тізімі
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