NEW METHOD OF DIFFERENTIAL DIAGNOSTICS OF UROGENITAL REACTIVE AND PSORIATIC ARTHRITIS


Дәйексөз келтіру

Толық мәтін

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Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The article presents the results of a examination of bioptates of lesions of 20 patients with stage II urgegenital reactive arthritis (UReA) and 40 patients with advanced psoriatic arthritis (PsA). The results of the histological examination indicated that there was no difference in the pattern of inflammation in both diseases, and there were no significant differences in immunoglobulin (Ig) deposits of different classes and the direct immunofluorescence (DIF) of lesions. However, using DIF method in UReA, IgG depositions of a diffuse nature were detected in the papillary and reticular dermis, and in PsA IgG deposits were detected only in the papillary dermis. It is also reported about the disappearance of IgG deposits in apparently healthy skin after the successful treatment of UReA. The obtained data on the important role of immune disorders in the pathogenesis of UReA and PsA, in particular about the significant differences in the nature of IgG deposits in the apparently healthy skin of these patients, can be used in the diagnosis and differential diagnosis of UReA and the possibility of using this method to evaluate the effectiveness of treatment of this disease.

Толық мәтін

Рұқсат жабық

Авторлар туралы

F. Paleev

National Medical Research Center for Cardiology

Yu. Molochkova

Moscow Regional Scientific Research Clinical Institute n.a. M.F. Vladimirsky

M. Petrova

Moscow Regional Scientific Research Clinical Institute n.a. M.F. Vladimirsky

Email: marina.s.petrova@gmail.com
Researcher at the Department of Dermatovenereology and Dermatooncology

Әдебиет тізімі

  1. Ревматология: национальное руководство / Под ред. Е.Л. Насонова, В.А. Насоновой. М., 2010. С. 348-67.
  2. Молочков В.А., Палеев Ф.Н., Молочков А.В., и др. Урогенитальный реактивный артрит М., 2014. 127 с. [Molochkov V.A., Paleev F.N., Molochkov A.V., et al. Urogenital reactive arthritis. Moscow, 2014. 127p.
  3. Villarial C., Wittum-Hadson J.A., Hudson A.P. Persistent Chlamydiae and chronic arthritis. Arthr. Res. 2002;4:5-9. (In Russ.)].
  4. Kumar S., Bhushan B., Ahluwalia R.S., et al. Reiter's disease: Circinate balanite as alone preceding prevention-succesfully treated with pemecrolimus 1% cream. Ind. J. Sex. Transm. Dis. 2015;36(1):70 3. doi: 10.4103/0253-7184.156733
  5. Whittum-Hudson J.A.,Gerard H.C.,Schumacher H.R., Hudson A.P. Pathogenesis of Chlamydia-associated arthritis. in: Bavoil P., Wyrick P. (ed.). Chlamydia genomic and pathogenesis. Horizon Bioscence, Inc. 2007. P 475-504
  6. Taylor-Robinson D., Keat A. Observation on Chlamydia trachomatis and other microbes in reactive arthritis. Int. J. STD AIDS. 2015;26(3):139 44. doi: 10.1177/0956462414533319
  7. Kuipers J.G., Scharmann K., Wollenhaup J., et al. Sensivities of PCR, MicroTrak, Chlamydia EIA, IDEIA, and PACE2 for purified Chlamydia trachomatis elementary bodies in urina, peripherial blood? peripheral blood leukocyte, and synovial fluid. J. Clin. Microbiol. 1995;33:3186-93.
  8. Молочков В.А., Ильин И.И. Хронический уретрогенный простатит. М.,2004.287c
  9. Meador R., Hsia E., Kitumnuaypong T., Schumacher H.R. TNF involvment and anti-TNF therapy of reactive and unclassified arthritis. Clin. Exp. Reumatol. 2002;20(6 Suppl. 28):130-34.
  10. Keller H., Wen J., Wang J., et al. Serum antibodies from patients with ankilosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Micobacterium tuberculosis hsp-60 gene. infect. immun. 1994;62:484-91.
  11. Молочков В.А. Урогенитальный хламидиоз. М., 2006. 208 c.
  12. Carter J.D., Hudson A.P. the evolving syory of chlamydial-induced reactive arthritis. Curr. Opin. Rheumatol. 2010;22:424-30. Doi: 10.1097/ BOR.0b013e32833a43a2.
  13. Rihl M., Klos A., Kohler L., Kulpers J.G. Reactive arthritis. Nest Pract. Res. Clin. Rheumatol. 2006;20:1119-37. Doi: 10.1016/ J. berh.2006.08.008.
  14. Ильин И.И., Ковалев Ю.Н. Вопросы профилактики и диспансеризации при урогенитальных артритах. Ревматология. 1985;2:66-70.
  15. Fox R., Calin A., Gerber R.C., Gibson D. The chronicity of symptoms and disability in Reiter's syndrome. An analysis of 131 consequtive patients. Ann. Intern. Med. 1979;91:190-93.
  16. Kerimovic-Morina D., Mladenovic V., Kicevac-Miljkovic A. Psoriatic sacroileitis and spondylitis. Eur. Congr. Rheumatol. 12-th. Abstr. Budapest, 1991. P. 89-91.
  17. Resnick D., Niwayama G. Psoritic arthritis/ Diagnosis of bone and joint disorders. Ed. Resnick D. Philadelphia: Saunders, 1995. P. 1075-102.
  18. Шубин С.В., Орлова О.Е., Сидельникова С.М. и др. Хламидии и болезнь Рейтера. Хламидийные инфекции/ Под ред. А.А. Шаткина. М., 1986. С. 73-6.
  19. Смирнов А.В., Мылов Н.М., Шубин С.В. Клинико-рентгенологическая характеристика урогенных артритов. Клиническая ревматология. 1994;4:22-4.
  20. Prohaska E., Obercriacher J., Hawel R., Petershofer H. Spinal involvement in chronic Reiter's syndrome. Z. Rheumatol. 1986;45(4):155-60.

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