Correction of age-related cognitive decline: new perspectives on an old problem
- Авторлар: Yakupov E.Z.1,2
-
Мекемелер:
- Kazan State Medical University
- Scientific Research Medical Complex “Your Health"
- Шығарылым: Том 26, № 13 (2019)
- Беттер: 63-67
- Бөлім: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/312387
- DOI: https://doi.org/10.18565/pharmateca.2019.13.63-67
- ID: 312387
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
With age, cognitive functions undergo significant changes: memory and learning ability decrease and “intellectual rigidity" appears. There are a number of studies proving the existence of the phenomenon of «age-associated memory impairment». W. Kral described benign senescent forgetfulness syndrome in 1962. This syndrome was characterized by isolated forgetfulness while maintaining criticism and intelligence. Unlike dementia, such a disorder is based on physiological involutional changes in the brain associated with normal aging, due to age-related changes and not affecting daily life. In recent years, various research teams in search of an optimal solution to the problem of age-related cognitive decline pay close attention to natural products with targeted action on nerve tissue and a high safety profile. One of such agents is the neuropeptide complex, the biologically active supplement Memoprove®*.
Толық мәтін
Авторлар туралы
Eduard Yakupov
Kazan State Medical University; Scientific Research Medical Complex “Your Health"
Email: ed_yakupov@mail.ru
MD, Professor, Head of the Department of Neurology, Neurosurgery and Medical Genetics
Әдебиет тізімі
- Hafington Post Why People Fear Dementia More Than They Do Cancer. 04/08/2014 07:23 BST.
- Захаров В.В. Всероссийская программа исследований эпидемиологии и терапии когнитивных расстройств в пожилом возрасте («Прометей»). Неврологический журнал. 2006;11:27-32.
- Crook T., Tinklenberg J., Yesavage J., et al. Effects of phosphatidylserine in age-associated memory impairment. Neurol. 1991;41:644-49. Doi: https://doi.org/10.1212/wnl.41.5.644.
- Koivisto K. Memory complaints in elderly. Neurology 1995;45:741-47.
- Fjell A.M., Walhoyd K.B. Structural brain changes in aging: courses, causes and cognitive consequences. RevNeurosci. 2011;21(3):187-221. Doi: https:// doi.org/10.1515/REVNEUR0.2010.21.3.187.
- Diagnostic and statistical manual of mental diseases. 5th ed. (DSM-V). London: American Psychiatric Association, 2013.
- Хананашвили М.М. Информационные неврозы. М.: Медицина, 1978. 118 с.
- McEntee W., Crook T. Serotonin, memory and the aging brain. Psychopharmacol. 1991;103:143-49. Doi: https://doi.org/10.1007/BF02244194.
- McEntee W., Crook T. Cholinergic function in the aged brain: Implications for treatment of memory impairments associated with aging. Behavioral Pharmacol. 1992;3:327-36.
- Eder P., Reinprecht I., Schreiner E., Scifitsch G., Windisch M. Increased density of glutamate receptor subunit 1 due to Cerebrolysin treatment: an immunohistochemical study of aged rats. Histochem J. 2001;33:605-12. Doi: https://doi. org/10.1023/a:1016394031947.
- Hartbauer B., Hutter-Paier B., Skofitsch G., Windisch M. Antiapoptic effects of the pep-tidergic drug Cerebrolysin on primary cultures of embryonic chick cortical neurons. J. Neural Transm. 2001;108:459-73. doi: 10.1007/s007020170067.
- Hutter-Paier B., Reininger-Gutmann B., Wronski R., et al. Long-term treatment of aged Long Evans rats with a dietary supplement containing neuroprotective peptides (N-PEP-12) to prevent brain aging: effects of three months daily treatment by oral gavage. J. Med Life. 2015;8(2):207-12.
- Alvarez X.A., Corzo L., Perez P., et al. Neuropeptide Dietary Supplement Enhances Cognitive Function and Activates Brain Bioelectrical Activity in Healthy Elderly Subjects. Methods Find Exp Clin Pharmacol. 2005;27(7):483-87. Doi: https://doi.org/10.1358/mf.2005.27.7. 914776.
- Hulette C.M., Welsh-Bohmer K.A., Murray M.G., et al. Neuropathological and Neuropsychological Changes in «Normal» Aging: Evidence for Preclinical Alzheimer's Disease in Cognitively Normal Individuals. J. Neuropathol Exp Neurol. 1998;57:1168-74. Doi: https:// doi.org/10.1097/00005072-199812000- 00009.
- Volc D., Alvarez A., Moessler H. Cognitive Effects of the Novel Neuroprotective Dietary Product N-PEP-12: Evidence from a Self-Assessment Study JATROS. Special Edition. 2005.
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