The effect of pregnancy and thyroid hormones on the occurrence and course of extrasystole

Мұқаба

Дәйексөз келтіру

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Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Background. The study of the effect of pregnancy hormones on the occurrence and course of extrasystolic arrhythmia is one of the most difficult issues in modern medicine.

Objective. Evaluation of the effect of chorionic gonadotropin, progesterone, thyroid hormones and type 1 diastolic dysfunction on the occurrence and course of ventricular extrasystole in pregnant women.

Methods. 32 pregnant women with ventricular extrasystole (Group 1) and 30 pregnant women without extrasystole (Group 2) without heart pathology, aged 19–38 years (mean age 29.8±2.4 years) were examined. Research methods included general clinical studies, electrocardiogram (ECG), echocardiography (EchoCG), 24-hour ECG monitoring, determination of the levels of chorionic gonadotropin, progesterone, and thyroid hormones.

Results. A close relationship (p<0.05) between chorionic gonadotropin and thyroid-stimulating hormone levels and extrasystole was revealed. A regression model predicting the course of extrasystolic arrhythmia in pregnant women with AF was constructed. It was found that the predictive value of the equation is 98.6%. The antiarrhythmic effect of the combined use of potassium preparations with magnesium was established.

Толық мәтін

Рұқсат жабық

Авторлар туралы

O. Vinogradova

Penza Institute for Postgraduate Medical Education – Branch Campus of RMACPE

Email: pgu-vb2004@mail.ru
ORCID iD: 0000-0002-9094-8772
Ресей, Penza

Fagim Rakhmatullov

Penza State University

Хат алмасуға жауапты Автор.
Email: pgu-vb2004@mail.ru
ORCID iD: 0000-0002-0253-6904

Dr.Sci. (Med.), Professor, Department of Internal Medicine, Medical Institute

Ресей, Penza

M. Ostanin

Penza Institute for Postgraduate Medical Education – Branch Campus of RMACPE

Email: pgu-vb2004@mail.ru
Ресей, Penza

R. Rakhmatullov

Penza State University

Email: pgu-vb2004@mail.ru
ORCID iD: 0000-0002-2157-544X
Ресей, Penza

Әдебиет тізімі

  1. Bokeria E.L. Fetal tachyarrhythmias: current state of the problem. Doktor.ru 2021;20(8):64–9. (In Russ.). doi: 10.31550/172-2378-2021-20-8-64-69.
  2. Strizhakova A.N., Ignatko I.V., Rodionova A.M. Fetal arrhythmias. M., 2021. (In Russ.).
  3. Arakelyants A.A., Morozova T.E., Barabanova E.A., Samokhi- na E.O. Structural and functional changes in the heart during pregnancy in women with cardiovascular diseases. Lechashchii vrach. 2021;7(24):18–23. (In Russ.). doi: 10.51793/OS.2021.24.7.004.
  4. ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J. 2018;39(34):3165–241. doi: 10.1093/eurheartj/ehy340ESC.
  5. Gorohova S.G., Morozova T.E., Arakeliants A.A. Algorithm for echocardiographic research in pregnant women. Rossiiskii kardiologicheskii zhurnal=Russ J Cardiol. 20182018;23(12):75–82. (In Russ.). doi: 10.15829/1560-4071-2018- 12-75-83.
  6. Diagnosis and treatment of cardiovascular diseases during pregnancy 2018. National recommendations. Rossiiskii kardiologicheskii zhurnal=Russ J Cardiol. 2018;3:91–134. (In Russ.). doi: 10.15829/1560-4071-2018-3-91-134.
  7. Katritsis D.G., Boriani G., Cosio F.G., et al. European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE). Europace. 2017;19(3):465–511. doi: 10.1093/europace/ euw301.

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Әрекет
1. JATS XML
2. Fig.1. Correlation between hCG and TSH levels in pregnant women with PVC

Жүктеу (59KB)
3. Fig.2. Correlation between the level of hCG and PVC in pregnant women with extrasystole

Жүктеу (59KB)
4. Fig.3. Correlation between the level of hCG with the ratio of the peak rate of early diastolic filling to the peak rate of late filling in pregnant women with PVC

Жүктеу (52KB)
5. Fig.4. Correlation between E/A peak ratios and the number of ESA cases

Жүктеу (49KB)

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