How has the approach to the asthma treatment changed in the recent years


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Modern pharmacotherapy of bronchial asthma passed from the therapeutic approach in accordance with the severity of the disease to implementation of two general concepts: disease control in some patients and decrease of the potential risks associated with the disease in all patients. To perform the latter task, administration of the best combinations of inhalation glucocorticosteroids and long-acting beta2-agonists in single inhaler for basic therapy and for needs is the most effective. To date, Symbicort with unique delivery system (Turbuhaler) is the exclusive drug providing the optimal effect in SMART mode (Symbicort Maintenance and Reliever Therapy).

Bibliografia

  1. Calhoun WJ, et al. J Allergy Clin Immunol 2003;112:1088-94.
  2. Suissa S, et al. NEJM 2000;343:332-36.
  3. O'Byrne MP, et al. Low Dose Inhaled Budesonide and Formoterol in Mild.
  4. Persistent Asthma. Am J Respir Crit Care Med 2001;164:1392-97.
  5. Pauwels RA, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med 1997;337:1405-11.
  6. Rabe KF, et al. Clinical management of asthma in 1999: the Asthma Insights and Reality in Europe (AIRE) study. Eur Respir J 2000;16:802-07.
  7. Bateman ED, et al. Am J Respir Crit Care Med 2004;170:836-44.
  8. GINA Report, Global Strategy for Asthma Management and Prevention. Published November 2006. Доступна по адресу http://www.ginasthma.org
  9. Bateman ED, et al. Stability of asthma control with regular treatment: an analysis of the Gaining Optimal Asthma controL (GOAL) study. Allergy 2008;63:932-38.
  10. Чучалин А.Г., Цой А.Н., Архипов В.В. и др. Бронхиальная астма в России: результаты национального исследования качества медицинской помощи больным бронхиальной астмой // Пульмонология. 2006. № 6. С. 94-102.
  11. Humbert M. Allergy 2007;62:95-101.
  12. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Full Report 2007. NIH Publication No. 07-4051:417 р.
  13. Bai TR, et al. Eur Respir J 2007;30:452-56.
  14. Foresi А, Catena E. CHEST 2000;117:440-46.
  15. Rabe KF, Pizzichini E, Bjorn Stallberg B, et al. Budesonide/Formoterol in a Single Inhaler for Maintenance and Relief in Mild-to-Moderate Asthma. Chest 2006;129:246-56.
  16. Scicchitano R, Aalbers R, Ukena D, et al. Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma. Curr Med Res Opin 2004;20(9):1403-18.
  17. O'Byrne PM, Bisgaard H, Godard PP, et al. Budesonide/Formoterol Combination Therapy as Both Maintenance and Reliever Medication in Asthma. American Journal of Respiratory and Critical Care Medicine 2005;171:129-36.
  18. Rabe KF, Atienza T, Magyar P, et al. Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study. Lancet 2006;368(9537):744-53.
  19. Vogelmeier C, D'Urzo A, Pauwels R, et. al. Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? Eur Respir J 2005;26(5):819-28.
  20. Kuna P, Peters MJ, Buhl R. Budesonide/formoterol as maintenance and reliever therapy reduces asthma exacerbations versus a higher maintenance dose of budesonide/formoterol or salmeterol/fluticasone. Abstract presented at the ERS Congress 2006.
  21. Bousquet J, et al. Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/fluticasone. Respiratory Medicine 2007;101:2437-46.
  22. Bateman ED, O'Byrne PM. Poster ERS 2008.
  23. Цой А.Н., Архипов В.В., Чапурин С.А. и др. Фармакоэкономическое исследование новой концепции применения Симбикорта у больных бронхиальной астмы // Пульмонология. 2007. № 3. C. 34-40.

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