Osobennosti lecheniya narusheniy tolerantnosti k glyukoze u patsientov s abdominal'no-vistseral'nym tipom ozhireniya na rannikh etapakh ego razvitiya

The article discusses the mechanisms of development of metabolic syndrome (MS), which are based on insulin resistance, and exacerbated by the development of “magnesium deficiency" and the activation of oxidative stress against the background of obesity. Based on personal experience of examination of 54 patients with MS at the early stages of its development, authors recommend to include incretin mimetics (exenatide), preparations of magnesium, and antioxidants in the complex therapy of MS, which allows more effective restoration of the sensitivity of insulin receptors, normalization of blood carbohydrate and lipid profiles, and achievement of target levels of blood pressure.

obesity, metabolic syndrome, insulin resistance, type 2 diabetes mellitus, incretins, exenatide