Clinical efficacy of Chondrogard in therapy of osteoarthrosis

This study was aimed to the evaluation of the efficacy and tolerability of chondroitin sulfate in different variants of osteoarthrosis (OA) and evaluation of radiographic parameters after first and repeated courses of treatment. The study included 99 patients with definite OA. The main group has received 20 injections of Chondrogard 2 ml intramuculary on alternate days, Nemulex 100 mg/day for 10 days; the control group has received standard care. For the assessment of the quality of therapy, dynamics of radiographic parameters of joints of the hands, knees, and hips in frontal, lateral, and axillary projections in the position of maximum extension in gonarthrosis were used; the lateral and medial tibiofemoral areas were evaluated. The results of the study led to the conclusion about the positive impact of Chondrogard on pathogenetic mechanisms of OA, as well as direct dependence of the efficacy of drug on the duration of therapy.

osteoarthrosis, pathogenesis, chondroitin sulfate, duration of therapy