MEKhANIZMY DEYSTVIYa PREPARATA TsEL' T NA PATOGENETIChESKIE PROTsESSY, LEZhAShchIE V OSNOVE RAZVITIYa OSTEOARTROZA
- Autores: Mar'yanovskiy A.A1
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Afiliações:
- Edição: Nº 19 (2015)
- Páginas: 58-62
- Seção: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/288359
- ID: 288359
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Resumo
This review is devoted to the analysis of the mechanisms of action of different classes of drugs on the pathogenesis of osteoarthrosis. The main advantages and disadvantages of selective and nonselective cyclooxygenase inhibitors are discussed. It is shown that, in contrast to non-steroidal anti-inflammatory drugs, the drug Zeel T has a dual mechanism of action (act both on cyclooxygenase and lipoxygenase). The review presents the results of studies confirming that such a dual inhibition allows to stop the pain and inflammation while avoiding lesions of structures of the digestive tract.
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