FROM HISTORY OF ENDOMETRIOSIS TO MODERN METHODS OF TREATMENT


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Resumo

Endometriosis is a common disease; approximately 176 million of women of reproductive age suffer from this disease in the world. An effective and safe drug therapy for endometriosis allows to reduce the need to perform radical surgery; also, it allows to preserve fertility. Specifically designed for the treatment of endometriosis, dienogest combines the properties of 19-nortestosterone (strong progesta-genic effect on the endometrium, a relatively short half-life, high bioavailability when administered orally), and progesterone derivatives (antiandrogenic effect, good tolerability, predominantly local effects). In a small dose (2 mg), it is effective to decrease endometrial lesions, relief of pain associated with endometriosis, including dysmenorrhea, premenstrual pain, dyspareunia, and diffuse pelvic pain; while long-term use it is as effective as agonists of gonadotropin-releasing hormone.

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Sobre autores

V. Balan

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Email: balan@freemail.ru
MD, Prof.

S. Orlova

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

A. Zhuravel

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

V. Ovchinnikova

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Yu. Titchenko

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

E. Tikhomirova

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Yu. Zlotnikova

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Z. Torshina

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

E. Levkovich

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

V. Ananyev

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

I. Rizhinashvili

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

I. Lazareva

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Yu. Belaya

SBHCI MR «Moscow Regional Scientific Research Institute of Obstetrics and Gynecology»

Bibliografia

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