LASER-INDUCED THERMOTHERAPY OF AIDS-ASSOCIATED KAPOSI'S SARCOMA

Background. Kaposi's sarcoma (KS) is the most common malignant neoplasm of homo- and bisexual men with acquired immunodeficiency syndrome (AIDS). Although widespread use of highly active antiretroviral therapy (HAART) leads to a decrease in the frequency of AIDS-associated KS and promotes regression of its skin manifestations, in some cases other methods may be required to treat such patients. Description of the clinical case. The article presents the case of the successful use of laser-induced thermotherapy (LITT) for a patient with AIDS-associated KS receiving HAART (indinavir+zidovudine+lamivudine), carried out for the 5 remaining papular elements with a diameter of 0.3 to 1.5 cm in 3 months from the HAART beginning. The procedures lasted for 10 to 30 minutes depending on the size of the focus. The LITT procedure was performed once and was well tolerated. On the 7-15th day, there were the pale pink areas of cicatricial atrophy and hyperpigmentation on the site of the former lesions, which disappeared 3 months after. Other papular and plaque manifestations of the KS at that time had not completely regressed. Conclusion. It is noted that the LITT method, which was previously used by the authors in the treatment of idiopathic and immunosuppressive KS, is well tolerated and can be used in the treatment of nodular elements of AIDS-associated KS.

AIDS-associated Kaposi's sarcoma, highly active antiretroviral therapy, laser-induced thermotherapy