Рамиприл: возможности применения при ишемической болезни сердца
- Авторы: Минушкина Л.О1
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Учреждения:
- УНМЦ УД Президента РФ
- Выпуск: № 14 (2012)
- Страницы: 84-89
- Раздел: Статьи
- URL: https://journals.eco-vector.com/2073-4034/article/view/279868
- ID: 279868
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Аннотация
В обзоре рассмотрены возможности использования ингибиторов ангиотензинпревращающего фермента в лечении больных ишемической болезнью сердца (ИБС). Отражены гемодинамические и нейрогуморальные эффекты препаратов этой группы, особенности фармакокинетики. Подробно разобраны исследования, касающиеся одного из препаратов данной группы -рамиприла. Описаны результаты исследований AIRE и HOPE, послуживших основой для включения рамиприла в рекомендации по лечению больных острым инфарктом миокарда и по вторичной профилактике среди больных ИБС с высоким риском осложнений. Приведены доказательства эффективности рамиприла при лечении инфаркта миокарда и возможные механизмы снижения риска осложнений.
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