АЦЕТИЛСАЛИЦИЛОВАЯ КИСЛОТА И ПЕРВИЧНАЯ ПРОФИЛАКТИКА: НОВЫЕ ВОЗМОЖНОСТИ

  • Авторы: Лагута П.С1
  • Учреждения:
    1. Институт клинической кардиологии им. А.Л. Мясникова, Российский кардиологический научно-производственный комплекс Минздрава РФ
  • Выпуск: № 15 (2017)
  • Страницы: 16-23
  • Раздел: Статьи
  • URL: https://journals.eco-vector.com/2073-4034/article/view/289969
  • ID: 289969

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Аннотация

Активация тромбоцитов и последующее тромбообразование играют ключевую роль в развитии и прогрессировании атеросклероза и его осложнений. Ацетилсалициловая кислота (АСК), чья клиническая эффективность и безопасность подтверждены многочисленными контролируемыми исследованиями и мета-анализами, и на сегодняшний день продолжает рассматриваться в качестве стандарта антитромботической терапии. Вместе с тем, несмотря на широкий и многолетний опыт использования АСК, сохраняются некоторые спорные вопросы относительно ее применения. Эффективность АСК при назначении больным высокого риска с целью снижения частоты инфаркта миокарда, инсульта и сосудистой смерти не вызывает сомнений. В то же время целесообразность ее использования у пациентов низкого/среднего риска для первичной профилактики сердечно-сосудистых событий не столь очевидна и требует тщательной оценки предполагаемой пользы и возможного риска от проведения подобной терапии.

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Об авторах

П. С Лагута

Институт клинической кардиологии им. А.Л. Мясникова, Российский кардиологический научно-производственный комплекс Минздрава РФ

Email: pavellaguta@yandex.ru
к.м.н., науч. сотр. лаборатории клинических проблем атеротромбоза Москва

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