CARBAPENEMS (IMIPENEM, MEROPENEM, DORIPENEM) IN THE TREATMENT OF NOSOCOMIAL PNEUMONIA: CURRENT STATE OF THE PROBLEM


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Nosocomial pneumonia (NP) is one of the most common hospital-acquired infections and leading cause of mortality among such infections. Adequate empirical antibiotic therapy plays defininge role in the successful outcome of NP. Carbapenems (imipenem/cilastatin, meropenem, doripenem) are recommended as first-line therapy for advanced NP and/or risk factors for multi-resistant microorganisms. This review is aimed to summarize data for the use of various carbapenems in the treatment of NP, their comparative clinical and pharmacoeconomic efficiency.

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