Primenenie Ksefokama (lornoksikama) u bol'n'kh osteoartrozom
- 作者: Anikin S.G1, Alekseeva L.I1
-
隶属关系:
- 期: 编号 7 (2013)
- 页面: 74-77
- 栏目: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/280977
- ID: 280977
如何引用文章
详细
The article discusses the problem of the treatment of patients with osteoarthrosis (OA). Among pharmaceutical treatments for OA, nonsteroidal anti-inflammatory drugs (NSAIDs) continue to occupy a leading position due to pronounced anti-inflammatory and analgesic effects, good tolerability and safety when properly used. One of the NSAID used for the treatment of OA is lornoxicam (Xefocam). This preparation refers to oxicams and is balanced inhibitor COX1/COX2. Xefocam (lornoxicam) is effective and safe NSAID for the treatment of patients with OA. The drug is well tolerated, comparable to other commonly used non-selective NSAIDs, and the emergence of new forms for intra-articular administration can further expand the therapeutic potential of this drug.
全文:
![受限制的访问](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
参考
- Фоломеева О.М., Амирджанова В.Н., Якушева Е.О. и др. Анализ структуры XIII класса болезней // Рос. ревматол. 1998. № 1. С. 2-7.
- Saase, van Romunde L, Cats A, et al. Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations. Ann Rheum Dis 1989;48(4):271-80.
- Goldring MB, Otero M. Inflammation in osteoarthritis. Curr Opin Rheumatol 2011;23(5): 471-78.
- Song IH, Burmester GR, Backhause M, et al. Knee osteoarthritis. Efficacy of a new method of contrast - enhanced musculoskeletal ultrasonography in detection of synovitis in patients with knee osteoarthritis in comparison with magnetic resonance imaging. Ann rheum dis 2008;1(67),19-25.
- Scanzello CR, Moskowitz NK, Gibofsky A. The post-NSAID era: what to use now for the pharmacologic treatment of pain and inflammation in osteoarthritis. Curr Rheumatol Rep 2008;10(1):49-56.
- Wolfe F, Zhao S, Lane N. Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. Arthritis Rheum 2000;43(2):378-85.
- Skjodt NM, Davies NM. Clinical pharmacokinetics of lornoxicam. A short half-life oxicam. Clin Pharmacokinet 1998;34(6): 421-28.
- Olkkola KT, Brunetto AV, Mattila MJ. Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents. Clin Pharmacokinet 1994;26(2):107-20.
- Ankier SI, Brimelow AE, Crome P, et al. Chlortenoxicam pharmacokinetics in young and elderly human volunteers. Postgrad Med J 1988;64(756):752-54.
- Balfour JA, Fitton A, Barradell LB. Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs 1996;51(4):639-57.
- Berry H, Bird HA, Black C, et al. A double blind, multicentre, placebo controlled trial of lornoxicam in patients with osteoarthritis of the hip and knee. Ann Rheum Dis 1992;51(2): 238-42.
- Kidd B, Frenzel W. A multicenter, randomized, double blind study comparing lornoxicam with diclofenac in osteoarthritis. J Rheumatol. 1996;23(9):1605-11.
- Nycomed. Xefocam® Монография // medi.ru. 2008. 03.
- Schroeder S, Heuser A, Tellmann A, et al. Local tolerance of intraarticular administration of lor-noxicam into the rabbit knee joint. Rheumatol Int 2012;32(9):2661-67.
- Цурко В.В., Балабанова Р.М., Олюнин ЮА. Внутрисуставное ведение лорноксикама: клинико-зксперементальное обоснование и оценка зффективности // Consilium medicum 2006. № 7. C. 115
- Дыбин С.Д., Маркова Н.Г., Широкова Л.Ю. и др. Зффективность ксефокама в лечении синовита коленных суставов у больных остеоартрозом и ревматоидным артритом с сопутствующим сахарным диабетом 1 типа / Тезисы докладов VII Российского национального конгресса "Человек и лекарство". M., 2000.
- Леганова Н.М., Денисова О.А. Оценка зффективности внутрисуставного введения ксефокама у больных гонартрозом, осложненным синовитом, с использованием артросонографии // Научно-практическая ревматология 2003. № 2. С. 61.
- Цурко В.В., Хитров Н.А., Агапова Л.А. Клиническая оценка внутрисуставного введения лорноксикама (ксефокама) у больных с ревматоидным артритом // Практич. мед. 2005. № 1 (10). С. 62-3.
补充文件
![](/img/style/loading.gif)