Disturbances of the autonomic innervation of the cardiovascular system and hemostasis: their role in the change of microcirculation in patients with type 2 diabetes mellitus

In the study including 260 women with type 2 diabetes mellitus, an assessment of changes in cardiovascular innervation, hemostasis, and clarification of their association with microcirculatory disturbances were performed. In most of these patients, the decrease in linear velocity of arteriolar blood flow and the violation of vascular reactivity were determined, which may be due to the presence of cardiovascular autonomic neuropathy and disorders in the hemostasis system towards hypoaggregation, intensifying against the background of severe decompensation of diabetes.

type 2 diabetes mellitus, women, cardiovascular autonomic neuropathy, arteriolar blood flow, platelet hyperaggregation, platelet hypoaggregation