EEG-characteristics of hemispheric ischemic stroke patients

Background. Modern ideas about the mechanisms of the damaging effect of acute cerebral ischemia are associated with an understanding of the complex relationships between the vascular supply and the morphofunctional state of the brain tissues. The evaluation of the bioelectrical activity of the cerebral cortex for assessment of the functional state of the central nervous system of patients with brain injury of various genesis is well known. The application of the method of quantitative analysis of the electroencephalogram (EEG) makes it possible to develop mathematical models of cerebral stroke of various localizations and genesis, and to evaluate their changes against the background of standard therapy. Objective. Assessment of the possibility of using quantitative electroencephalography (qEEG) in the evaluation of the functional state of the brain of ischemic stroke (IS) patients compared with the neuropsychological data. Methods. The study included 30 patients with IS in the middle cerebral artery (MCA) territory. EEG recording was performed for 30 minutes on the first day of the disease. Results. The results of study indicated that post-stroke cognitive and anxiety-depressive disorders are detected already in the peracute and acute periods of IS. The mathematical analysis of the EEG in patients with IS in the MCA territory has revealed a decrease in the power level of all rhythms both in the affected and intact hemisphere, a decrease in inter-hemispheric coherence, and an increase in the integral index, the most pronounced in the temporal and central regions in the affected hemisphere. The level of coherence in all frequency ranges in the ipsilateral temporal region correlates with the neuropsychological data. Conclusion. Neuropsychological data are comparable with EEG data, which allows to make a judgment about the primary lesion of the mediobasal structures of the temporal region.

ischemic stroke, neuropsychological examination, electroencephalography, coherence