Current trends in drug therapy for resectable locally advanced gastric cancer

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Дәйексөз келтіру

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Аннотация

Gastric cancer is one of the most pressing problems in modern oncology. Surgery is currently the main treatment for resectable gastric cancer, but overall survival rates remain unsatisfactory. To date, combination therapy is the standard approach. Modern drug therapy, in addition to chemotherapy, includes targeted and immunotherapy, and it has changed significantly over the past few years. At the same time, perioperative chemotherapy regimens differ. In recent years, perioperative therapy using new agents such as targeted drugs and immune checkpoint inhibitors (ICIs) has also been investigated with promising results. Perioperative therapy has become an integral part of treatment strategies and requires further study. This review demonstrates modern perioperative therapy regimens, their recent achievements and presents future prospects.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Konstantin Titov

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; People’s Friendship University of Russia (RUDN University)

Хат алмасуға жауапты Автор.
Email: ks-titov@mail.ru
ORCID iD: 0000-0003-4460-9136
SPIN-код: 7795-6512

Dr. Sci. (Med.), Professor, Leading Researcher, S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Professor, Department of Oncology and Roentgenology named after Academician V.P. Kharchenko, Medical Institute, People’s Friendship University of Russia (RUDN University)

Ресей, Moscow; Moscow

Igor Andreytsev

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center

Email: ks-titov@mail.ru
ORCID iD: 0000-0002-6756-9555

Dr. Sci. (Med.), Leading Researcher

Ресей, Moscow

Dmitry Grekov

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Russian Medical Academy of Continuous Professional Education

Email: ks-titov@mail.ru
ORCID iD: 0000-0001-8391-1210
SPIN-код: 6841-7128

Cand. Sci. (Med.), Associate Professor, Chief Physician, S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Associate Professor, Department of Surgery, Faculty of Surgery, Russian Medical Academy of Continuous Professional Education

Ресей, Moscow; Moscow

Aleksandr Kuzmenko

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center

Email: ks-titov@mail.ru
ORCID iD: 0000-0002-1488-7795

Surgeon, Oncosurgical Department No. 72

Ресей, Moscow

Sergey Lebedev

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Russian Medical Academy of Continuous Professional Education

Email: ks-titov@mail.ru
ORCID iD: 0000-0001-5366-1281

Dr. Sci. (Med.), Associate Professor, Deputy Chief Physician for Oncology, S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center; Professor, Department of Surgery, Faculty of Surgery, Russian Medical Academy of Continuous Professional Education

Ресей, Moscow; Moscow

Natalia Podzolkova

Russian Medical Academy of Continuous Professional Education

Email: ks-titov@mail.ru
ORCID iD: 0000-0001-9183-7030

Dr. Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology

Ресей, Moscow

Antonio Chekini

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center

Email: ks-titov@mail.ru
ORCID iD: 0000-0001-9065-4726
SPIN-код: 3114-0517

Cand.Sci. (Med.), Senior Researcher

Ресей, Moscow

Nikolay Sokolov

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center

Email: ks-titov@mail.ru

Cand. Sci. (Med.), Head of the Oncology Department of Antitumor Drug Therapy No. 15

Ресей, Moscow

Alisa Minenkova

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center

Email: ks-titov@mail.ru
ORCID iD: 0000-0001-6996-2724
Scopus Author ID: 57221414403

Physician, Resident in Surgery, Department of Surgery, Faculty of Surgery

Ресей, Moscow

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