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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Systemic Hypertension</journal-id><journal-title-group><journal-title xml:lang="en">Systemic Hypertension</journal-title><trans-title-group xml:lang="ru"><trans-title>Системные гипертензии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-082X</issn><issn publication-format="electronic">2542-2189</issn><publisher><publisher-name xml:lang="en">Intermedservice Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">28954</article-id><article-id pub-id-type="doi">10.26442/SG28954</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Combined pharmacotherapy for arterial hypertension: a view through the 2013 clinical practice guidelines</article-title><trans-title-group xml:lang="ru"><trans-title>Комбинированная фармакотерапия артериальной гипертензии: взгляд через призму клинических рекомендаций 2013 года</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rodionov</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Родионов</surname><given-names>Антон Владимирович</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доц. каф. факультетской терапии №1 лечебного фак-та</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО Первый МГМУ им. И.М.Сеченова Минздрава РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2013</year></pub-date><volume>10</volume><issue>2</issue><issue-title xml:lang="en">VOL 10, NO2 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 10, №2 (2013)</issue-title><fpage>5</fpage><lpage>8</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2075-082X/article/view/28954">https://journals.eco-vector.com/2075-082X/article/view/28954</self-uri><abstract xml:lang="en"><p>The paper considers major changes in approaches to treating arterial hypertension in the context of the 2013 clinical guidelines on hypertension of the European Society of Cardiology/European Society of Arterial Hypertension. Prominence is given to a differentiated approach to combined pharmacotherapy, including the use of a fixed-dose lercanidipine/enalapril combination.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассматриваются основные изменения в подходах к лечению артериальной гипертензии с позиции клинических рекомендаций по данному заболеванию Европейского общества кардиологов/Европейского общества артериальной гипертензии 2013 г. Основное внимание уделено дифференцированному подходу к комбинированной фармакотерапии, в том числе с применением фиксированной комбинации лерканидипина и эналаприла.</p></trans-abstract><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>treatment</kwd><kwd>fixed-dose combination</kwd><kwd>lercanidipine</kwd><kwd>enalapril</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>лечение</kwd><kwd>фиксированная комбинация</kwd><kwd>лерканидипин</kwd><kwd>эналаприл</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Mancia G, de Backer G, Dominiczak A et al. ESH - ESC Task Force on the Management of Arterial Hypertension. 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH - ESC Task Force on the Management of Arterial Hypertension. 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