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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Systemic Hypertension</journal-id><journal-title-group><journal-title xml:lang="en">Systemic Hypertension</journal-title><trans-title-group xml:lang="ru"><trans-title>Системные гипертензии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-082X</issn><issn publication-format="electronic">2542-2189</issn><publisher><publisher-name xml:lang="en">Intermedservice Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">28989</article-id><article-id pub-id-type="doi">10.26442/SG28989</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Sindrom obstruktivnogo apnoe sna i disfunktsiya endoteliya</article-title><trans-title-group xml:lang="ru"><trans-title>Синдром обструктивного апноэ сна и дисфункция эндотелия</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Galitsin</surname><given-names>Pavel Vasil'evich</given-names></name><name xml:lang="ru"><surname>Галицин</surname><given-names>Павел Васильевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>мл. науч. сотр. отд. гипертонии Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><email>pgalicin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aksenova</surname><given-names>Anna Vladimirovna</given-names></name><name xml:lang="ru"><surname>Аксенова</surname><given-names>Анна Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, мл. науч. сотр. отд. гипертонии Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Elfimova</surname><given-names>Evgeniya Mikhaylovna</given-names></name><name xml:lang="ru"><surname>Елфимова</surname><given-names>Евгения Михайловна</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отд. гипертонии Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ishankhodzhaeva</surname><given-names>Gul'bakhor Rakhmatullaevna</given-names></name><name xml:lang="ru"><surname>Ишанходжаева</surname><given-names>Гульбахор Рахматуллаевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>докторант, канд. мед. наук, отд. гипертонии Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Balakhonova</surname><given-names>Tat'yana Valentinovna</given-names></name><name xml:lang="ru"><surname>Балахонова</surname><given-names>Татьяна Валентиновна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., рук. лаб. ультразвуковых методов исследования сосудов отд. новых методов диагностики Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Litvin</surname><given-names>Aleksandr Yur'evich</given-names></name><name xml:lang="ru"><surname>Литвин</surname><given-names>Александр Юрьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, рук. лаб. апноэ сна Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chazova</surname><given-names>Irina Evgen'evna</given-names></name><name xml:lang="ru"><surname>Чазова</surname><given-names>Ирина Евгеньевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>проф., чл.-кор. РАМН, рук. отд. гипертонии, дир. Института клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБУ РКНПК Минздрава России, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2013</year></pub-date><volume>10</volume><issue>3</issue><issue-title xml:lang="en">VOL 10, NO3 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 10, №3 (2013)</issue-title><fpage>85</fpage><lpage>91</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2075-082X/article/view/28989">https://journals.eco-vector.com/2075-082X/article/view/28989</self-uri><abstract xml:lang="ru"><p>Статья посвящена вопросам взаимосвязи синдрома обструктивного апноэ сна (СОАС) и сердечно-сосудистых заболеваний. Более подробно описан вопрос взаимодействия дисфункции эндотелия (ДЭ) и СОАС. Обсуждены современные представления о механизмах развития артериальной гипертензии при СОАС. Приводятся как доказательные данные, так и мнения экспертов. Рассмотрены вопросы влияния постоянного положительного давления в дыхательных путях на ДЭ.</p></abstract><kwd-group xml:lang="ru"><kwd>синдром обструктивного апноэ сна</kwd><kwd>дисфункция эндотелия</kwd><kwd>артериальная гипертензия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Malhotra A, White D.P. Obstructive sleep apnoea. Lancet 2002; 360: 237–45.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bray G.A. Pathophysiology of obesity. Am J Clin Nutr 1992; 55: 488–94.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Young T, Palta M, Dempsey J et al. The occurrence of sleep - disordered breathing among middle - aged adults. 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