<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Systemic Hypertension</journal-id><journal-title-group><journal-title xml:lang="en">Systemic Hypertension</journal-title><trans-title-group xml:lang="ru"><trans-title>Системные гипертензии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-082X</issn><issn publication-format="electronic">2542-2189</issn><publisher><publisher-name xml:lang="en">Intermedservice Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">29122</article-id><article-id pub-id-type="doi">10.26442/SG29122</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comparison of vectorcardiographic parameters with structural-functional state of the right ventricle in patients with pulmonary hypertension</article-title><trans-title-group xml:lang="ru"><trans-title>Сопоставление векторкардиографических параметров со структурно-функциональным состоянием правого желудочка у пациентов с легочной гипертензией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Blinova</surname><given-names>E V</given-names></name><name xml:lang="ru"><surname>Блинова</surname><given-names>Елена Валентиновна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, науч. сотр. отд. новых методов диагностики ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sakhnova</surname><given-names>T A</given-names></name><name xml:lang="ru"><surname>Сахнова</surname><given-names>Тамара Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотр. отд. новых методов диагностики ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><email>tamara-sahnova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Saidova</surname><given-names>M A</given-names></name><name xml:lang="ru"><surname>Саидова</surname><given-names>Марина Абдулатиповна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, рук. лаб. ультразвуковых методов исследования ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Loskutova</surname><given-names>A S</given-names></name><name xml:lang="ru"><surname>Лоскутова</surname><given-names>Анна Сергеевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела новых методов исследования ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ryabykina</surname><given-names>G V</given-names></name><name xml:lang="ru"><surname>Рябыкина</surname><given-names>Галина Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., вед. науч. сотр. отд. новых методов диагностики ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Arkhipova</surname><given-names>O A</given-names></name><name xml:lang="ru"><surname>Архипова</surname><given-names>Ольга Александровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, мл. науч. сотр. лаб. легочной гипертензии отд. гипертонии ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Martynyuk</surname><given-names>T V</given-names></name><name xml:lang="ru"><surname>Мартынюк</surname><given-names>Тамила Витальевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, рук. лаб. легочной гипертензии отд. гипертонии ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><email>trukhiniv@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Trunov</surname><given-names>V G</given-names></name><name xml:lang="ru"><surname>Трунов</surname><given-names>Владимир Григорьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. тех. наук, ст. науч. сотр. лаб. обработки биоэлектрической информации ИППИ им. А.А.Харкевича</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aidu</surname><given-names>E A</given-names></name><name xml:lang="ru"><surname>Айду</surname><given-names>Эдуард Альфредович</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. тех. наук, ст. науч. сотр. лаб. обработки биоэлектрической информации ИППИ им. А.А.Харкевича</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chazova</surname><given-names>I E</given-names></name><name xml:lang="ru"><surname>Чазова</surname><given-names>Ирина Евгеньевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>чл.-кор. РАН, д-р мед. наук, проф., дир. ИКК им. А.Л.Мясникова ФГБУ РКНПК</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ Российский кардиологический научно-производственный комплекс Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">A.A.Kharkevich Institute for Information Transmission Problems of RAS</institution></aff><aff><institution xml:lang="ru">ФГБУН Институт проблем передачи информации им. А.А.Харкевича РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2015</year></pub-date><volume>12</volume><issue>4</issue><issue-title xml:lang="en">VOL 12, NO4 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 12, №4 (2015)</issue-title><fpage>57</fpage><lpage>60</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/2075-082X/article/view/29122">https://journals.eco-vector.com/2075-082X/article/view/29122</self-uri><abstract xml:lang="en"><p>Changes of the vectrocardiographic ventricular gradient (VG) in patients with pulmonary arterial hypertension (PAH) are indicative of right ventricular (RV) overload and may be used to assess its severity. The study aim was to evaluate interrelations between vectrocardiographic VG, spatial QRS-T angle and echocardiographic parameters of structural-functional state of the RV.The following parameters were assessed in 30 PAH patients: RV dimensions; tricuspid annular plane systolic excursion (TAPSE); RV fractional area change (FAC); RV peak systolic annular velocity (TDI-S’), and longitudinal strain (LS). VG and spatial QRS-T angle were calculated using the orthogonal leads derived from standard echocardiography.Spatial component VG-Y had moderate negative correlation with LS (r=-0.62; p &lt;0.005); VG magnitude, VG-X and VG-Y had positive correlations with FAC (r from 0.50 to 0.65; p &lt;0.005); VG magnitude and VG-Y had positive correlations with TDI-S’ (0.58 and 0.53; p &lt;0.005); spatial QRS-T angle had negative correlation with TAPSE (r=-0.59; p &lt;0.005), FAC (r=-0.66; p &lt;0.005) and TDI-S’ (r=-0.67); p &lt;0.005.In patients with severe PAH, VG and spatial QRS-T angle correlate not only with RV dimensions and pulmonary artery pressure, but with parameters of RV systolic function.</p></abstract><trans-abstract xml:lang="ru"><p>Изменения векторкардиографического желудочкового градиента (VG) у пациентов с легочной артериальной гипертензией (ЛАГ) являются показателем перегрузки правого желудочка (ПЖ) и могут использоваться для оценки ее тяжести. Целью исследования было оценить взаимосвязь векторкардиографических показателей VG и пространственный угол QRS-T с эхокардиографическими показателями структурно-функционального состояния ПЖ.У 30 пациентов с ЛАГ были оценены размеры ПЖ; амплитуда экскурсии фиброзного кольца трикуспидального клапана (TAPSE), относительное изменение площади ПЖ (FAC), систолическая скорость ПЖ (TDI-S’); продольная деформация (LS). VG и пространственный угол QRS-T рассчитывали с использованием ортогональных отведений, синтезированных из стандартной электрокардиографии.Пространственная компонента VG-Y имела умеренную отрицательную корреляцию с LS (r=-0,62; p &lt;0,005); амплитуда VG и компоненты VG-Х и VG-Y - положительные корреляции с FAC (r от 0,50 до 0,65; р &lt;0,005); амплитуда VG и компонента VG-Y - положительные корреляции с TDI-S’ (r 0,58 и 0,53; p &lt;0,005), пространственный угол QRS-T - отрицательные корреляции с TAPSE (r=-0,59; p &lt;0,005), FAC (r=-0,66; p &lt;0,005) и TDI-S’ (r=-0,67); p &lt;0,005.У лиц с тяжелой ЛАГ VG и пространственный угол QRS-T коррелируют не только с размерами ПЖ и давлением в легочной артерии, но и с параметрами систолической функции ПЖ.</p></trans-abstract><kwd-group xml:lang="en"><kwd>vectorcardiography</kwd><kwd>ventricular gradient</kwd><kwd>echocardiography</kwd><kwd>right ventricular systolic function</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>векторкардиография</kwd><kwd>желудочковый градиент</kwd><kwd>эхокардиография</kwd><kwd>систолическая функция правого желудочка</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Galiè N, Hoeper M.M, Humbert M et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009; 30: 2493-537.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Vonk Noordegraaf A, Galiè N. The role of the right ventricle in pulmonary arterial hypertension. Eur Respir Rev 2011; 20 (122): 243-53.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Badano L.P, Ginghina C, Easaw J et al. Right ventricle in pulmonary arterial hypertension: haemodynamics, structural changes, imaging, and proposal of a study protocol aimed to assess remodelling and treatment effects. Eur J Echocardiogr 2010; 11 (1): 27-37.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Macfarlane P.W, Okin P.M, Lawrie T.D.V, Milliken J.A. Enlargement and Hypertrophy. In: P.W.Macfarlane, A.Van Oosterom, O.Pahlm, P.Kligfield, M.Janse, J.Camm, editors. Comprehensive electrocardiology. London: Springer Verlag; 2011; p. 607-44.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Henkens I.R, Mouchaers K.T, Vonk-Noordegraaf A et al. Improved ECG detection of presence and severity of right ventricular pressure load validated with cardiac magnetic resonance imaging. Am J Physiol Heart Circ Physiol 2008; 294 (5): H2150- H2157.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Kamphuis V.P, Haeck M.L, Wagner G.S et al. Electrocardiographic detection of right ventricular pressure overload in patients with suspected pulmonary hypertension. J Electrocardiol 2014; 47 (2): 175-82.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Scherptong R.W, Henkens I.R, Kapel G.F et al. Diagnosis and mortality prediction in pulmonary hypertension: the value of the electrocardiogram - derived ventricular gradient. J Electrocardiol 2012; 45(3): 312-8.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Rudski L.G, Lai W.W, Afilalo J et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010; 23 (7): 685-713.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Kors J.A, Van Herpen G, Sittig A.C, Van Bemmel J.H. Reconstruction of the Frank vectorcardiogram from standard electrocardiographic leads: diagnostic comparison of different methods. Eur Heart J 1990; 11: 1083-92.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Scherptong R.W, Henkens I.R, Man S.C et al. Normal limits of the spatial QRS-T angle and ventricular gradient in 12-lead electrocardiograms of young adults: dependence on sex and heart rate. J Electrocardiol 2008; 41 (6): 648-55.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Voulgari C, Pagoni S, Tesfaye S, Tentolouris N. The spatial QRS-T angle: implications in clinical practice. Curr Cardiol Rev 2013; 9 (3): 197-210.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Man S, Rahmattulla C, Maan A.C et al. Role of the vectorcardiogram - derived spatial QRS-T angle in diagnosing left ventricular hypertrophy. J Electrocardiol 2012; 45 (2): 154-60.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Bacharova L, Estes H, Bang L et al. The first statement of the Working Group on Electrocardiographic Diagnosis of Left Ventricular Hypertrophy. J Electrocardiol 2010; 43 (3): 197-9.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Bacharova L, Estes E.H, Bang L.E et al. Second statement of the working group on electrocardiographic diagnosis of left ventricular hypertrophy. J Electrocardiol 2011; 44 (5): 568-70.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Jr. Estes E.H. ECG manifestations of left ventricular electrical remodelling. J Electrocardiol 2012; 45 (6): 612-6.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Hill J.A. Hypertrophic reprogramming of the left ventricle: translation to the ECG. J Electrocardiol 2012; 45 (6): 624-9.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Bacharova L. Left ventricular hypertrophy: disagreements between increased left ventricular mass and ECG-LVH criteria: the effect of impaired electrical properties of myocardium. J Electrocardiol 2014; 47 (5): 625-9.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Blyth K.G, Kinsella J, Hakacova N et al. Quantitative estimation of right ventricular hypertrophy using ECG criteria in patients with pulmonary hypertension: A comparison with cardiac MRI. Pulm Circ 2011; 1 (4): 470-4.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Siddiqui A.M, Samad Z, Hakacova N et al. The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum - type atrial septal defect in adults. J Electrocardiol 2010; 43 (2): 161-6.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Motoji Y, Tanaka H, Fukuda Y et al. Efficacy of right ventricular free - wall longitudinal speckle - tracking strain for predicting long - term outcome in patients with pulmonary hypertension. Circ J 2013; 77 (3): 756-63.</mixed-citation></ref></ref-list></back></article>
