Systemic HypertensionSystemic HypertensionСистемные гипертензии2075-082X2542-2189Intermedservice Ltd2958910.26442/2075-082X_15.1.6-20ArticlesСтатьиReview ArticleClinical manual for diagnosis, prevention and treatment of cardiovascular complications of cancer therapy. Parts VI-VIIРуководство по диагностике, профилактике и лечению сердечно-сосудистых осложнений противоопухолевой терапии. Части VI-VIIChazovaI YeЧазоваИрина Евгеньевна

акад. РАН, д-р мед. наук, проф., рук. отд. гипертонии, дир., зам. ген. дир. по научной работе

TyulyandinS AТюляндинСергей Алексеевич

д-р мед. наук, проф., зав. отд-нием клинической фармакологии и химиотерапии

VitseniaM VВиценяМарина Вячеславна

канд. мед. наук, науч. сотр. отд. амбулаторных лечебно-диагностических технологий

marinavitsenya@gmail.comPanchenkoE PПанченкоЕлизавета Павловна

д-р мед. наук, проф., рук. отд. клинических проблем атеротромбоза

FedotkinaYu AФедоткинаЮлия Александровна

канд. мед. наук, науч. сотр. отд. клинических проблем атеротромбоза

PoltavskayaM GПолтавскаяМария Георгиевна

д-р мед. наук, проф. каф. профилактической и неотложной кардиологии

GilyarovM YuГиляровМихаил Юрьевич

д-р мед. наук, проф. каф. профилактической и неотложной кардиологии, зам. глав. врача по терапии, рук. Регионального сосудистого центра

MartynyukT VМартынюкТамила Витальевна

д-р мед. наук, проф., рук. отд. легочной гипертензии и заболеваний сердца

OvchinnikovA GОвчинниковАртем Германович

д-р мед. наук, вед. науч. сотр. отд. амбулаторных лечебно-диагностических технологий ФГБУ «НМИЦ кардиологии»

SteninaM BСтенинаМарина Борисовна

д-р мед. наук, вед. науч. сотр. отд-ния клинической фармакологии и химиотерапии ФГБУ «НМИЦ онкологии им. Н.Н.Блохина»

TrophimovaO PТрофимоваОксана Петровна

д-р мед. наук, вед. науч. сотр. радиологического отд-ния, проф. каф. онкологии

AgeevF TАгеевФаиль Таипович

д-р мед. наук, проф., рук. отд. амбулаторных лечебно-диагностических технологий

A.L.Myasnikov Institute of Clinical Cardiology National Medical Research Center of Cardiology of the Ministry of Health of the Russian FederationИКК им. А.Л.Мясникова, ФГБУ «НМИЦ кардиологии»N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationФГБУ «НМИЦ онкологии им. Н.Н.Блохина»A.L.Myasnikov Institute of Clinical Cardiology National Medical Research Center of Cardiology of the Ministry of Health of the Russian FederationФГБУ «НМИЦ кардиологии»I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationФГАОУ ВО «Первый МГМУ им. И.М.Сеченова»I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationФГАОУ ВО «Первый МГМУ им. И.М.Сеченова», ГБУЗ «ГКБ №1 им. Н.И.Пирогова»N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationФГБУ «НМИЦ онкологии им. Н.Н.Блохина», ФГБОУ ДПО РМАНПОRussian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian FederationФГБУ «НМИЦ кардиологии»A.L.Myasnikov Institute of Clinical Cardiology National Medical Research Center of Cardiology of the Ministry of Health of the Russian Federation15032018151VOL 15, NO1 (2018)ТОМ 15, №1 (2018)62009042020Copyright ©; 2018, Consilium MedicumCopyright ©; 2018, ООО "Консилиум Медикум"2018Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://journals.eco-vector.com/2075-082X/article/view/29589

Advances in treatment have led to improved survival of patients with cancer but have also resulted in untoward side effects associated with treatment. Cardiovascular diseases are one of the most frequent of these side effects. Myocardial dysfunction and heart failure, myocardial ischaemia, arrhythmias, arterial hypertension, thromboembolic disease and other cardiovascular complications can interfere with the efficacy of treatment, decrease quality of life, or impact the actual survival of the patient with cancer. This manual discusses concepts for timely diagnosis, intervention, and surveillance of patients treated with cardiotoxic cancer therapies. In this part оf manual we discuss the diagnostic, prevention and treatment aspects of cancer therapy-related thromboembolism and complications of radiotherapy.

Достижения в лечении онкологических заболеваний привели к повышению выживаемости больных со злокачественными новообразованиями. В то же время противоопухолевая терапия сопряжена с риском развития побочных эффектов, среди которых сердечно-сосудистые осложнения занимают лидирующие позиции. Дисфункция левого желудочка и сердечная недостаточность, артериальная гипертония, ишемия миокарда, нарушения ритма сердца, тромбоэмболии и другие сердечно-сосудистые осложнения могут препятствовать проведению жизненно важной противоопухолевой терапии, снижать выживаемость и качество жизни больных. В представленном руководстве отражены диагностические и терапевтические подходы к ведению больных онкологического профиля, получающих потенциально кардиотоксичную противоопухолевую терапию. Представленные части руководства посвящены вопросам диагностики, профилактики и лечения тромбоэмболических осложнений, связанных с противоопухолевой терапией, и осложнений лучевой терапии.

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