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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Clinical nephrology</journal-id><journal-title-group><journal-title xml:lang="en">Clinical nephrology</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническая нефрология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-3594</issn><issn publication-format="electronic">2414-9322</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">273930</article-id><article-id pub-id-type="doi">10.18565/nephrology.2022.1.69-72</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Dialysis-dependent acute kidney injury in a multidisciplinary hospital: a retrospective analysis of fatal outcomes</article-title><trans-title-group xml:lang="ru"><trans-title>Диализзависимое острое почечное повреждение в многопрофильном стационаре: ретроспективный анализ летальных исходов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Grigoryeva</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Григорьева</surname><given-names>Елена Вячеславовна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, assistant of professor of hospital therapy department</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры госпитальной терапии лечебного факультета</p></bio><email>lek133@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Voloshinova</surname><given-names>Elena V.</given-names></name><name xml:lang="ru"><surname>Волошинова</surname><given-names>Елена Викторовна</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, assistant of professor of hospital therapy department</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры госпитальной терапии лечебного факультета</p></bio><email>voloshinovaelena@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tolmazova</surname><given-names>Olga N.</given-names></name><name xml:lang="ru"><surname>Толмазова</surname><given-names>Ольга Николаевна</given-names></name></name-alternatives><bio xml:lang="en"><p>nephrologist</p></bio><bio xml:lang="ru"><p>врач-нефролог</p></bio><email>o.n.razumova@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shesterkina</surname><given-names>Ylia V.</given-names></name><name xml:lang="ru"><surname>Шестеркина</surname><given-names>Юлия Викторовна</given-names></name></name-alternatives><bio xml:lang="en"><p>resident of hospital therapy department</p></bio><bio xml:lang="ru"><p>ординатор кафедры госпитальной терапии лечебного факультета</p></bio><email>grachenok123@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Horkina</surname><given-names>Irina Y.</given-names></name><name xml:lang="ru"><surname>Хоркина</surname><given-names>Ирина Юрьевна</given-names></name></name-alternatives><bio xml:lang="en"><p>pathologist</p></bio><bio xml:lang="ru"><p>врач-патологоанатом</p></bio><email>irenhor@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saratov State Medical University named after V.I. Razumovsky</institution></aff><aff><institution xml:lang="ru">ФГБОУ во «Саратовский ГМУ им. В.И. Разумовского» Минздрава РФ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Regional Clinical Hospital, Saratov</institution></aff><aff><institution xml:lang="ru">ГУЗ «Областная клиническая больница», Саратов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2022</year></pub-date><volume>14</volume><issue>1</issue><issue-title xml:lang="en">VOL 14, NO1 (2022)</issue-title><issue-title xml:lang="ru">ТОМ 14, №1 (2022)</issue-title><fpage>69</fpage><lpage>72</lpage><history><date date-type="received" iso-8601-date="2023-02-22"><day>22</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО «Бионика Медиа»</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2075-3594/article/view/273930">https://journals.eco-vector.com/2075-3594/article/view/273930</self-uri><abstract xml:lang="en"><p>Objective. to assess the mortality structure in patients with dialysis-dependent acute kidney injury (AKi). material and methods. a retrospective analysis of 47 medical records of deceased patients with stage 3 aki was carried out. results. In 2017 161 patients, admitted to Saratov regional hospital, were diagnosed with stage 3 aki, 47 of them died, the mortality rate was 29.2%. 37 (78%) patients developed aki in the hospital. 39 (83%) patients were treated in intensive care units (icu). the main causes of aki were acute surgical pathology and sepsis. one third of the patients had a multiple cause aki. Risk factors were identified in 76.6% of patients. The main causes of death were brain or pulmonary edema. Conclusion. Dialysis-dependent aki is one of the aspects of multiple organ dysfunction in serious comorbid patients and is a predictor of an unfavorable outcome. In this regard, much attention should be paid to early detection of risk factors and prevention of aki.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования: оценить структуру летальности среди пациентов с диализзависимым острым почечным повреждением (опп). Материал и методы. Проведен ретроспективный анализ 47 медицинских карт умерших пациентов с диагнозом опп 3-й стадии. Результаты. в 2017 г. в ГУЗ «областная клиническая больница» (Саратов)161 пациенту установлено опп 3-й стадии, из них умерли 47 больных, летальность составила 29,2%. У 37 (78%) УМЕРШИХ ПАЦИЕНТОВ ОПП РАЗВИЛОСЬ В СТАЦИОНАРЕ, 39 (83%) пациентов находились на лечении в отделениях реанимации и интенсивной терапии. Основные причины опп - острая хирургическая патология и сепсис. У трети пациентов имел место смешанный генез опп. У 76,6% выявлены факторы риска. Основные причины летального исхода - отек вещества головного мозга, отек легких. Заключение. Диализзависимое опп - одно из проявлений полиорганной дисфункции у тяжелых коморбидных пациентов, которое служит предиктором неблагоприятного исхода. в связи с этим следует уделять большое внимание раннему выявлению факторов риска и профилактике развития опп.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute kidney injury</kwd><kwd>hemodialysis</kwd><kwd>mortality</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острое почечное повреждение</kwd><kwd>гемодиализ</kwd><kwd>летальность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Королев В.А., Молчанов В.И. Острая почечная недостаточность и острое повреждение почек: некоторые исторические аспекты синдромов. Вестник Балтийского федерального университета им. И. Канта. Серия: Естественные и медицинские науки. 2017;3:58-70.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Батюшин М.М., Руденко Л.И., Кастанаян А.А., Воробьев Б.И. 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