Epidemiology and Infectious Diseases. Current ItemsEpidemiology and Infectious Diseases. Current Items2226-69762414-9640Bionika Media28799710.18565/epidem.2022.12.4.68-71Research ArticleCrimean hemorrhagic fever in a COVID-19 patient: a clinical caseAbuovaGuldzhan N.Can. Med. Sci., Head, Department of Infectious Diseases and Dermatovenerologydr.abuova@gmail.comPshenichnayaNatalia Yu.MD, Deputy Director for Clinical and Analytical Worknatalia-pshenichnaya@yandex.ruBerdalievaFarida A.Can. Med. Sci., Associate Professor, Department of Infectious Diseases and Dermatovenerologyfberdalieva@mail.ruPolukchiTatiana V.Assistant Lecturer, Department of Infectious Diseases and Dermatovenerologytatyana_polukchi@mail.ruAlievDaulet S.Assistant Lecturer, Department of Infectious Diseases and Dermatovenerologydauletaliev68@mail.ruSadykhovaDana K.Assistant Lecturer, Department of Infectious Diseases and Dermatovenerologydanoka.kz@mail.ruAlievEldar Yu.Highest-Category Resuscitatoreldar_aliev_84@inbox.ruLizinfeldIrina A.Advisoririnalizinfeld@gmail.comAkimkinVasily G.Academician of the Russian Academy of Sciences, MD, Director-South Kazakhstan Medical AcademyCentral Research Institute of EpidemiologyShymkent City Infectious Diseases Hospital15042022124687126022023Copyright © 2022, Bionika Media2022Crimean hemorrhagic fever (CHF) is endemic in the southern regions of the Republic of Kazakhstan. During the COVID-19 pandemic, there are cases of CHF and COVID-19 coinfection, presenting substantial difficulties in both the diagnosis and treatment of these patients. CHF cases and outbreaks are an additional threat during the pandemic due to the severity of the course, the difficulty of differential diagnosis, and the poor prognosis of CHF and COVID-19. The 2020-2021 summer as the most active season for the incidence of CHF in the city of Shymkent and the Turkestan Region coincided with the peaks in the waves of the COVID-19 pandemic, whereas the similarity of the symptoms of the diseases involved difficulties in establishing a diagnosis. The paper describes clinical case of a patient with severe CHF in the presence of clinical signs of coronavirus infection, COVID-19-associated pneumonia, with a favorable outcome, who has been treated in the Shymkent City Infectious Diseases Hospital. Timely diagnosis and etiotropic therapy with ribavirin, replacement treatment with blood drugs and the use of immunized convalescent plasma could achieve a favorable outcome.COVID-19Crimean hemorrhagic feverCOVID-19intoxicationthrombocytopeniacoagulopathyhemorrhagic syndromepandemicКрымская геморрагическая лихорадкаинтоксикациятромбоцитопениякоагулопатиягеморрагический синдромпандемия[Fletcher T.E., Abuova G., Ahmeti S., Al-Abri S.S., Asik Z., Atilla A. et al. Infection prevention and control practice for Crimean-Congo hemorrhagic fever-A multi-center crosssectional survey in Eurasia. PLoS One 2017; 12(9): e0182315. doi: 10.1371/journal.pone.0182315. PMID: 28886039; PMCID: PMC5590734][BUyUktuna S., Hasbek M., Oksuz C., Baysal C., Oz M., Elaldi N. et al. Kirim Kongo Kanamali Ate§i Hastasinda COVID-19 Ko-enfeksiyonu: Bir Olgu Sunumu [COVID-19 Co-infection in a patient with Crimean Congo Hemorrhagic Fever: A Case Report]. Mikrobiol. Bul. 2021; 55(3): 445-51. (Turkish). doi: 10.5578/mb.20219813. PMID: 34416809][Butt M.H., Ahmad A., Misbah S., Mallhi T.H., Khan Y.H. Crimean-Congo hemorrhagic fever and Eid-Ul-Adha: A potential threat during the COVID-19 pandemic. J. Med. Virol. 2021; 93(2): 618-9. doi: 10.1002/jmv.26388. PMID: 32749713; PMCID: PMC7436305][Pazarli A.C., Parlak Z., Ekiz T. COVID-19 and Crimean-Congo Hemorrhagic Fever: Similarities and Differences. Heart Lung. 2020; 49(6): 892-3. doi: 10.1016/j.hrtlng.2020.05.013. PMID: 32536567; PMCID: PMC7266772][Ozaras R., Dilek A., Sunbul M., Leblebicioglu H. Association between Crimean-Congo hemorrhagic fever (CCHF) and coronavirus disease 2019 (COVID-19): A systematic review. Infect. Control Hosp. Epidemiol. 2021; 12. doi: 10.1017/ice.2021.388. PMID: 34462024; PMCID: PMC8438420][Dulger A.C., Yakari§ik M., Uzun Y.E., §ahin A.M. Treatment of Crimean-Congo Haemorrhagic Fever by Favipiravir in a Patient with Novel Coronavirus Co-Infection. Eur. J. Case Rep. Int. Med. 2020; 7(12): 002042. doi: 10.12890/2020_002042. PMID: 33457366; PMCID: PMC7806293][Albayrak A., Alay H., Yilmaz S.I. Comorbidity of Crimean-Congo Hemorrhagic Fever and COVID-19. Rev. Soc. Bras. Med. Trop. 2021; 54: e0429. doi: 10.1590/0037-8682-0429 2021. PMID: 34586291; PMCID: PMC8463030]