LATENT HBV INFECTION


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The paper provides an analytical literature review characterizing the current status of the problem of latent HBV infection. It shows the heterogeneity of the states combined into the concept of latent HBV infection. The main causes and epidemiological, clinical, and laboratory characteristics of latent hepatitis B virus infection are outlined.

Full Text

Restricted Access

About the authors

G. Yu NIKITINA

S.P. Botkin City Clinical Hospital

Email: g.u.nikitina@gmail.ru
Moscow

S. L VOZNESENSKY

Peoples' Friendship University of Russia

Moscow

D. N MAULETOVA

Peoples' Friendship University of Russia

Moscow

References

  1. Онищенко Г.Г. О санитарно-эпидемиологической обстановке в Российской Федерации в 2009 году: Государственный доклад. М.: Федеральный центр гигиены и эпидемиологии Роспотребнадзора; 2010. 456 с.
  2. Вирусные гепатиты в Российской Федерации. Аналитический обзор. Вып. 8. Под ред. В.И.Покровского, А.Б.Жебруна. СПб.: НИИЭМ им. Пастера, 2011. 116 с.
  3. Chu C.M., Hung S.J., Lin J. et al. Natural history of hepatitis B e antigen to antibody seroconversion in patients with normal serum aminotransferase levels. Am. J. Med. 2004; 116: 829-834.
  4. Allain J.P. Occult hepatitis B virus infection. J. Hepatitis Annual 2005; 2(1): 14-30.
  5. Морозов И.А., Ильченко Л.Ю., Громова Н.И. и др. Проблемы скрытой инфекции, вызванной вирусом гепатита В. Рос. журн. гастроэнтерол., гепатол., колопроктол. 2012; 22(4): 58-66.
  6. Raimondo G., Pollicino T., Cacciola I., Squadrito G. Occult hepatitis B virus infection. J Hepatol 2007, 46:160-170.
  7. Raimondo G., Pollicino T., Squadrito G. What is the clinical impact of occult hepatitis B virus infection? Lancet 2005; 365: 638-640.
  8. Chaudhuri V., Tayal R., Nayak B. et al. Occult hepatitis B virus infection in chronic liver disease fulllength genome and analysis of mutant surface promoter. Gastroenterology 2004; 127: 1356-1371.
  9. Chemin I., Trepo C. Clinical impact of occult HBV infections. J. Clin. Virol. 2005; 34: S15-S21.
  10. Fabrizi F., Messa P. G., Lunghi G. et al. Occult hepatitis B virus infection in dialysis patients: a multicentre survey. Aliment Pharmacol. Ther. 2005; 21: 1341-1347.
  11. Siagris D., Christofidou M., Triga K. et al. Occult hepatitis B virus infection in hemodialysis patients with chronic HCV infection. J. Nephrol. 2006; 19: 327-333.
  12. Filippini P., Coppola N., Pisapia R. et al. Impact of occult hepatitis B virus infection in HIV patients naive for antiretroviral therapy. AIDS 2006; 20: 1253-1260.
  13. Mphahlele M.J., Lukhwareni A., Burnett R.J. et al. High risk of occult hepatitis B virus infection in HIV-positive patients from South Africa. J. Clin. Virol. 2006; 35: 14-20.
  14. Owusu-Ofori S., Temple J., Sarkodie F. et al. Pre-donation screening of blood donors with rapid tests: Implementation and efficacy of a novel approach to blood safety in resource-poor settings. Transfusion 2005; 45: 133-140.
  15. Бацких С.Н., Теплинская Н.П., Исаков В.А. и др. Серопозитивная латентная HBV-инфекция у доноров крови. Инфекц. бол. 2007; 5(4): 12-14.
  16. Minuk G.Y., Sun D.F., Uhanova J. et al. Occult hepatitis B virus infection in a North American community-based population. J. Hepatol. 2005; 42: 480-485.
  17. Kim S.M., Lee K.S., Park C.J. et al. Prevalence of occult HBV infection among subjects with normal serum ALT levels in Korea. J. Infect. 2006; 54(2): 185-191.
  18. Samuel D., Forns X., Berenguer M. et al. Report of the monothematic EASL conference on liver transplantation for viral hepatitis (Paris, France, January 12—14, 2006). J. Hepatol. 2006; 45: 127—143.
  19. De Feo T.M., Poli F., Mozzi F. et al. Risk of transmission of hepatitis B virus from anti-HBC positive cadaveric organ donors: a collaborative study. Transpl Proc. 2005; 37: 1238— 1239.
  20. Onozawa M., Hashino S., Izumiyama K. et al. Progressive disappearance of anti-hepatitis B surface antigen antibody and reverse seroconversion after allogeneic hematopoietic stem cell transplantation in patients with previous hepatitis B virus infection. Transplantation 2005; 79: 616—619.
  21. Hui C.K., Cheung W.W., Zhang H.Y. et al. Kinetics and risk of de novo hepatitis B infection in HBsAg-negative patients undergoing cytotoxic chemotherapy. Gastroenterology 2006; 131: 59—68.
  22. Donato F., Gelatti U., Limina R.M., Fattovich G. Southern Europe as an example of interaction between various environmental factors: a systematic review of the epidemiologic evidence. Oncogene 2006; 25: 3756—3770.
  23. Yotsuyanagi H., Hashidume K., Suzuki M. et al. Role of hepatitis B virus in hepatocarcinogenesis in alcoholics. Alcoholism Clin. Exper. Res. 2004; 28: 181S—185S.
  24. Squadrito G., Pollicino T., Cacciola I. et al. Occult hepatitis B virus infection is associated with the development of hepatocellular carcinoma in chronic hepatitis C patients. Cancer 2006; 106: 1326—1330.
  25. Maynard M., Parvaz P., Durantel S. et al. Sustained HBs seroconversion during lamivudine and adefovir dipivoxil combination therapy for lamivudine failure. J. Hepatol. 2005; 42: 279—281.
  26. Zoulim F. New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA. J. Hepatol. 2005; 42: 302—308.
  27. Pollicino T., Belloni L., Raffa G. et al. Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones. Gastroenterology 2006; 130: 823—837.
  28. Pollicino T., Raffa G., Costantino L. et al. Molecular and functional analysis of occult hepatitis B virus isolates from patients with hepatocellular carcinoma. Hepatology 2007; 45: 277—285.
  29. Zaaijer H.L., Torres P., Ontanon A. et al. Multiple surface antigen mutations in five blood donors with occult hepatitis B virus infection. J. Med. Virol. 2008; 80: 1344—1349.
  30. Hass M., Hannoun C., Kalinina T. et al. Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigennegative individuals. Hepatology 2005; 42: 93—103.
  31. Van Hemert F.J., Zaaijer H.L., Berkhout B., Lukashov V.V. Occult hepatitis B infection: an evolutionary scenario. J. Virology 2008; 5: 146.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2012 Bionika Media